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托珠单抗诱发的新冠病毒病患者巨细胞病毒性结肠炎

Tocilizumab-induced cytomegalovirus colitis in a patient with COVID-19.

作者信息

Khatib Mohamad Y, Shaik Karimulla S, Ahmed Amna A, Alwraidat Mohammad A, Mohamed Ahmed S, Abou Kamar Mohamad R, Sharaf Eldean Mouhammad Z, Aldaraiseh Bashar K, Nashwan Abdulqadir J

机构信息

Critical Care Unit Hazm Mebaireek General Hospital (HMGH) Hamad Medical Corporation (HMC) Doha Qatar.

Department of Infectious Diseases Communicable Disease Center (CDC) Hamad Medical Corporation (HMC) Doha Qatar.

出版信息

Clin Case Rep. 2020 Nov 12;9(1):148-152. doi: 10.1002/ccr3.3487. eCollection 2021 Jan.

DOI:10.1002/ccr3.3487
PMID:33489151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7813092/
Abstract

The authors urge clinicians to observe for early signs of CMV reactivation in patients presenting with gastrointestinal bleeding and intestinal perforation after receiving tocilizumab or other immunosuppressive therapy as a treatment for COVID 19. Early recognition of CMV infection and treatment will prevent life-threatening bleeding and mortality.

摘要

作者敦促临床医生，对于接受托珠单抗或其他免疫抑制疗法治疗新冠病毒病后出现胃肠道出血和肠穿孔的患者，要留意巨细胞病毒再激活的早期迹象。早期识别巨细胞病毒感染并进行治疗可预防危及生命的出血和死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/059e34b9c7b9/CCR3-9-148-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/a6b54f598dc0/CCR3-9-148-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/c26d0cc71abf/CCR3-9-148-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/2aa0a14ad3c0/CCR3-9-148-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/366d2647fc01/CCR3-9-148-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/efb200a47e50/CCR3-9-148-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/059e34b9c7b9/CCR3-9-148-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/a6b54f598dc0/CCR3-9-148-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/c26d0cc71abf/CCR3-9-148-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/2aa0a14ad3c0/CCR3-9-148-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06a2/7813092/059e34b9c7b9/CCR3-9-148-g006.jpg

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A Practical Review of Cytomegalovirus in Gastroenterology and Hepatology.胃肠病学和肝病学中巨细胞病毒的实用综述
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