Mandal Shobha, Shah Ravindra, Lowry Philip
Internal Medicine, Guthrie Robert Packer Hospital, Sayre, USA.
Internal Medicine, Spinal Pain and Rehabilitation Medicine PC, New York, USA.
Cureus. 2020 Dec 15;12(12):e12095. doi: 10.7759/cureus.12095.
Pure red cell aplasia (PRCA) is a rare condition leading to erythroid bone marrow failure. Parvovirus is one of the rare causes of PRCA in older adults. We present a 73-year-old man on high dose prednisone who presented with rapid functional decline and shortness of breath and was found to have normocytic normochromic anemia with low reticulocyte counts. On further workup, he was found to have elevated immunoglobulin M (IgM) titer of parvovirus B-19 antibody. The patient was managed with supportive care with blood transfusion, hydration and had improvement in his symptoms.
纯红细胞再生障碍性贫血（PRCA）是一种导致红系骨髓衰竭的罕见病症。细小病毒是老年人PRCA的罕见病因之一。我们报告一例73岁男性，正在接受高剂量泼尼松治疗，出现快速功能衰退和呼吸急促，发现有正细胞正色素性贫血且网织红细胞计数低。进一步检查发现，他的细小病毒B19抗体免疫球蛋白M（IgM）滴度升高。该患者接受了输血、补液的支持性治疗，症状有所改善。
