Anderson Kristi Bøgh, Søgaard-Andersen Erik, Aleksyniene Ramune, Frandsen Anna Poulsgaard
Department of Pathology, Aalborg University Hospital, Ladegaardsgade 3, 9000 Aalborg, Denmark.
Department of Obstetrics and Gynecology, Aalborg University Hospital, Reberbansgade 15, 9000 Aalborg, Denmark.
Case Rep Womens Health. 2020 Dec 26;29:e00282. doi: 10.1016/j.crwh.2020.e00282. eCollection 2021 Jan.
The case of a 56-year-old woman with a fibroid uterus who developed utero-cutaneous fistula is presented. The woman was para 0, had an unremarkable medical history, and had no prior diagnosis of a gynecologic pathology, no operative interventions involving the uterine wall or any other risk factor for fistula. Abdominal examination revealed an abdominal mass with overlying deep, purulent ulceration. F-FDG PET/CT scan was consistent with uterine leiomyoma, but a differential diagnosis of sarcoma was considered due to the presence of the fistula, patchy increased FDG uptake of the tumor and several mildly enlarged lymph nodes bilaterally in the inguinal and iliac region. Hysterectomy with bilateral salpingo-oophorectomy was performed. Histological diagnosis was of leiomyoma with focal bizarre atypia, degenerative and metaplastic changes and utero-cutaneous fistula. To the best of our knowledge, this is the first case report describing a benign leiomyoma forming a fistula between the uterus and abdominal surface.
本文报告了一例56岁患有子宫肌瘤的女性发生子宫皮肤瘘的病例。该女性未生育,既往病史无特殊,之前未诊断出妇科疾病,未进行过涉及子宫壁的手术干预或任何其他导致瘘管的危险因素。腹部检查发现腹部有一肿物,其上有深部脓性溃疡。F-FDG PET/CT扫描结果与子宫平滑肌瘤相符,但由于存在瘘管、肿瘤FDG摄取呈斑片状增加以及双侧腹股沟和髂区有几个轻度肿大的淋巴结,故考虑肉瘤的鉴别诊断。遂行子宫切除术及双侧输卵管卵巢切除术。组织学诊断为平滑肌瘤,伴有局灶性奇异异型性、退行性和化生改变以及子宫皮肤瘘。据我们所知,这是第一例描述良性平滑肌瘤在子宫与腹壁之间形成瘘管的病例报告。