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Perspective of gene therapy with replication competent viruses.

作者信息

Maemondo Makoto

机构信息

Division of Pulmonary Medicine, Allergy and Rheumatology, Iwate Medical University, Iwate, Japan.

出版信息

Transl Lung Cancer Res. 2020 Dec;9(6):2511-2513. doi: 10.21037/tlcr-20-547.

DOI:10.21037/tlcr-20-547
PMID:33489812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7815362/
Abstract
摘要

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A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study.一项关于塞内卡谷病毒(NTX-010)与安慰剂治疗广泛期小细胞肺癌(ES-SCLC)患者的随机双盲 II 期研究,这些患者在至少四个周期铂类化疗后病情稳定或有缓解:中北部癌症治疗组(Alliance)N0923 研究。
J Thorac Oncol. 2020 Jan;15(1):110-119. doi: 10.1016/j.jtho.2019.09.083. Epub 2019 Oct 9.
2
Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.炭疽毒素受体1是塞内卡山谷病毒的细胞受体。
J Clin Invest. 2017 Aug 1;127(8):2957-2967. doi: 10.1172/JCI93472. Epub 2017 Jun 26.
3
Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group.塞内卡山谷病毒(NTX-010)用于复发/难治性实体瘤儿童的I期试验:儿童肿瘤协作组报告
Pediatr Blood Cancer. 2015 May;62(5):743-50. doi: 10.1002/pbc.25269. Epub 2014 Oct 12.
4
Docetaxel plus trans-tracheal injection of adenoviral-mediated p53 versus docetaxel alone in patients with previously treated non-small-cell lung cancer.多西紫杉醇联合经气管内注射腺病毒介导的 p53 与单纯多西紫杉醇治疗既往治疗的非小细胞肺癌患者的比较。
Cancer Gene Ther. 2011 Jun;18(6):444-9. doi: 10.1038/cgt.2011.15. Epub 2011 Apr 1.
5
Phase I clinical study of Seneca Valley Virus (SVV-001), a replication-competent picornavirus, in advanced solid tumors with neuroendocrine features.具有神经内分泌特征的晚期实体瘤患者中复制型小核糖核酸病毒(SVV-001)的 I 期临床研究。
Clin Cancer Res. 2011 Feb 15;17(4):888-95. doi: 10.1158/1078-0432.CCR-10-1706. Epub 2011 Feb 8.
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Adenovirus-mediated wild-type p53 gene transfer in combination with bronchial arterial infusion for treatment of advanced non-small-cell lung cancer, one year follow-up.腺病毒介导的野生型p53基因转移联合支气管动脉灌注治疗晚期非小细胞肺癌,一年随访
J Zhejiang Univ Sci B. 2009 May;10(5):331-40. doi: 10.1631/jzus.B0820248.
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Directed evolution generates a novel oncolytic virus for the treatment of colon cancer.定向进化产生了一种用于治疗结肠癌的新型溶瘤病毒。
PLoS One. 2008 Jun 18;3(6):e2409. doi: 10.1371/journal.pone.0002409.
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Seneca Valley virus, a systemically deliverable oncolytic picornavirus, and the treatment of neuroendocrine cancers.塞内卡山谷病毒,一种可全身递送的溶瘤微小核糖核酸病毒,与神经内分泌癌的治疗
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Intravascular adenoviral agents in cancer patients: lessons from clinical trials.癌症患者中的血管内腺病毒制剂:来自临床试验的经验教训。
Cancer Gene Ther. 2002 Dec;9(12):979-86. doi: 10.1038/sj.cgt.7700539.