Carter Lucy, Mankad Aditi
CSIRO Synthetic Biology Future Science Platform, Brisbane, QLD, Australia.
CSIRO Land & Water, Brisbane, QLD, Australia.
Front Bioeng Biotechnol. 2021 Jan 7;8:622221. doi: 10.3389/fbioe.2020.622221. eCollection 2020.
Discussions about the responsible advancement of synthetic biology science are at fever pitch. Commentators from across the globe are calling for greater integrated science investments and more inclusive governance processes in the development and implementation of these potentially disruptive technologies. We take stock of the promises and realities of science integration by sharing our experiences of embarking on this very challenge in Australia. We conclude by offering suggestions for bringing about the enabling conditions for improved integration across the natural and social sciences. Four key actions are articulated to help pivot synthetic biology toward a more integrated scientific endeavor: (a) formalizing inclusivity from inception to project conclusion; (b) valuing differing philosophical positions as a strength rather than a barrier; (c) accepting that integration takes persistence and communication but is immensely rewarding; and (d) promoting meaningful interactions, such as pursuing joint opportunities, co-designing and co-publishing research. We argue that these actions are key enablers for realizing science integration in synthetic biology.
关于合成生物学科学负责任发展的讨论正进行得如火如荼。来自全球各地的评论家呼吁在这些具有潜在颠覆性的技术的开发和实施过程中，进行更大规模的综合科学投资，并建立更具包容性的治理流程。我们通过分享在澳大利亚应对这一挑战的经验，来评估科学整合的前景与现实情况。我们在结尾处就如何创造有利条件以促进自然科学与社会科学的更好整合提出了建议。阐述了四项关键行动，以帮助使合成生物学转向更综合的科学努力：(a) 从项目启动到结束都将包容性形式化；(b) 将不同的哲学立场视为一种优势而非障碍；(c) 认识到整合需要坚持和沟通，但回报巨大；(d) 促进有意义的互动，例如寻求联合机会、共同设计和共同发表研究成果。我们认为这些行动是实现合成生物学科学整合的关键推动因素。
