Parekh Akarsh, Zhang Howard
Department of Medicine, Summa Health Systems, Barberton, OH.
Northeast Ohio Medical University, Rootstown, OH.
ACG Case Rep J. 2021 Jan 19;8(1):e00528. doi: 10.14309/crj.0000000000000528. eCollection 2021 Jan.
Propofol is a widely used sedative for gastrointestinal endoscopic procedures. Drug-induced pancreatitis is a relatively rare disease possibly because of poor recognition. Propofol-induced pancreatitis is an extremely rare phenomenon. We present a 22-year-old healthy man who underwent esophagogastroduodenoscopy with propofol as a sedative. Soon after, he developed acute upper gastrointestinal symptoms and was diagnosed with pancreatitis. His prolonged hospital course was complicated with necrotizing pancreatitis, acute respiratory distress syndrome, septic shock, and other end-organ damages. We hope to increase awareness of a life-threatening adverse event of a commonly used anesthetic such as propofol.
丙泊酚是一种广泛用于胃肠内镜检查的镇静剂。药物性胰腺炎是一种相对罕见的疾病，可能是因为认识不足。丙泊酚诱导的胰腺炎是一种极其罕见的现象。我们报告一名22岁的健康男性，他在丙泊酚镇静下接受了食管胃十二指肠镜检查。此后不久，他出现了急性上消化道症状，并被诊断为胰腺炎。他的住院病程延长，并发坏死性胰腺炎、急性呼吸窘迫综合征、感染性休克和其他终末器官损害。我们希望提高对丙泊酚这种常用麻醉剂危及生命的不良事件的认识。
