Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region.
Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region.
BMJ Paediatr Open. 2021 Jan 12;5(1):e000898. doi: 10.1136/bmjpo-2020-000898. eCollection 2021.
To explore risk factors associated with non-typhoidal gastroenteritis in young children in Hong Kong.
A case-control study.
Paediatrics wards at three public hospitals in Hong Kong.
Cases were children aged above 30 days to below 5 years hospitalised for gastroenteritis at three public hospitals in Hong Kong with culture confirmed non-typhoidal infection. Controls were age-matched (±2 months) children admitted for a reason other than gastroenteritis.
A face-to-face interview by using standardised questionnaire on exposures 3 days prior to illness. Adjusted OR (aORs) and 95% CIs were calculated using multivariable logistic regression.
A total of 102 cases and 204 age-matched controls were included in the analysis. Multivariable logistic regression revealed that having food purchased from places other than a supermarket, that is, from wet market/restaurant/farm (aOR, 2.64; 95% CI, 1.03 to 6.77; p=0.044) was a significant risk factor for non-typhoidal infection. Having a household member with gastroenteritis symptoms (aOR, 2.03; 95% CI, 0.94 to 4.39; p=0.072) was of borderline significance and playing at a children's indoor playroom was a protective factor (aOR, 0.28; 95% CI, 0.09 to 0.85; p=0.024).
Consumption of food purchased from places other than a supermarket was the identified determinant factor for non-typhoidal gastroenteritis in Hong Kong. Parents/caregivers should be alerted to this risk when choosing foods for their young children. The protective effect of playing in an indoor playroom could be confounded by socioeconomic factors and further investigation is required to better understand its potential implication. There was some support for person-to-person transmission and good family hygiene needs to be emphasised.
探讨香港婴幼儿非伤寒性肠胃炎的相关危险因素。
病例对照研究。
香港三间公立医院的儿科病房。
病例为在香港三间公立医院因肠胃炎住院的 30 天以上 5 岁以下儿童，培养证实为非伤寒性感染。对照组为因其他原因住院的年龄匹配（±2 个月）儿童。
采用标准化问卷对发病前 3 天的暴露情况进行面对面访谈。采用多变量逻辑回归计算调整后的比值比（aOR）和 95%可信区间。
共纳入 102 例病例和 204 例年龄匹配的对照组进行分析。多变量逻辑回归显示，从超市以外的地方购买食物，即从湿货市场/餐馆/农场购买食物（aOR，2.64；95%可信区间，1.03 至 6.77；p=0.044）是非伤寒性感染的显著危险因素。家中有肠胃炎症状的家庭成员（aOR，2.03；95%可信区间，0.94 至 4.39；p=0.072）为边缘显著，在儿童室内游乐室玩耍为保护因素（aOR，0.28；95%可信区间，0.09 至 0.85；p=0.024）。
在香港，从超市以外的地方购买食物是非伤寒性肠胃炎的确定决定因素。当父母/照顾者为其年幼子女选择食物时，应注意这一风险。在室内游乐室玩耍的保护作用可能受到社会经济因素的影响，需要进一步调查以更好地了解其潜在意义。有一些证据表明人与人之间存在传播，因此需要强调良好的家庭卫生。
