Lopes de Pontes T, Pinheiro Amador Dos Santos Pessanha F, Freire Junior R C, Pfrimer K, da Cruz Alves N M, Fassini P G, Almeida O L S, Moriguti J C, da Costa Lima N K, Ferreira Santos J L, Ferriolli E
Tatiane Lopes de Pontes, Ribeirão Preto Medical School, University of São Paulo, Avenida Bandeirantes, 3900, Ribeirão Preto, São Paulo 14049-900, Brazil, Telephone number: +55(16)3315-3370. E-mail:
J Nutr Health Aging. 2021;25(2):201-208. doi: 10.1007/s12603-020-1482-5.
Higher total energy expenditure in free living conditions, regardless of any activity, has been strongly associated with a lower risk of mortality in healthy older adults. Also, a good performance in physical and functional tests is a marker of good functional prognosis. However, it is not yet clear what is the association between total energy expenditure and the performance in physical and functional tests. The objective of this study was to verify the association between the total energy expenditure of older adults measured by doubly labelled water and the performance in functional tests.
Cross-sectional study.
Fifty-six older people were recruited from health services linked to the participating institutions.
Socio-demographic, anthropometric and clinical characteristics were assessed through the application of a structured questionnaire. Body composition was evaluated by isotopic dilution of deuterium oxide and functional status was assessed by the gait speed test, 6-minute walk test and handgrip strength. Total energy expenditure (GET) was assessed using the doubly labelled water method and the physical activity profile was verified using an activity monitor based on accelerometery.
The results showed that the highest total energy expenditure correlated with the best performance in the gait speed tests (r = 0.266; p = 0.047), 6-minute walk test (r = 0.424; p = 0.001) and maximum handgrip strength (r = 0.478; p = 0.000). Multivariate regression analysis in a model adjusted for sex and fat-free mass revealed an association between total energy expenditure and the 6-minute walk test (ß = 1.790; t = 2.080; p = 0.044) and the number of sedentary events ( ß = 6.389; t = 2.147; p = 0.038).
The results of this study suggest that, in clinical practice, older individuals with lower gait speed, worse performance in the 6-minute walk test and lower handgrip strength, may have lower total energy expenditure, being the stimulus for its increase important for the prevention of possible problems related to low energy expenditure.
在自由生活条件下，无论进行何种活动，较高的总能量消耗都与健康老年人较低的死亡风险密切相关。此外，身体和功能测试中的良好表现是良好功能预后的标志。然而，总能量消耗与身体和功能测试表现之间的关联尚不清楚。本研究的目的是验证用双标水测量的老年人总能量消耗与功能测试表现之间的关联。
横断面研究。
从与参与机构相关的卫生服务机构招募了56名老年人。
通过应用结构化问卷评估社会人口统计学、人体测量学和临床特征。通过氧化氘的同位素稀释评估身体成分，并通过步态速度测试、6分钟步行测试和握力评估功能状态。使用双标水法评估总能量消耗（GET），并使用基于加速度计的活动监测器验证身体活动概况。
结果表明，最高的总能量消耗与步态速度测试（r = 0.266；p = 0.047）、6分钟步行测试（r = 0.424；p = 0.001）和最大握力（r = 0.478；p = 0.000）中的最佳表现相关。在对性别和去脂体重进行调整的模型中进行的多变量回归分析显示，总能量消耗与6分钟步行测试（β = 1.790；t = 2.080；p = 0.044）和久坐事件数量（β = 6.389；t = 2.147；p = 0.038）之间存在关联。
本研究结果表明，在临床实践中，步态速度较低、6分钟步行测试表现较差和握力较低的老年人可能总能量消耗较低，增加总能量消耗对预防与低能量消耗相关的可能问题具有重要意义。
