Ustinov A S, Lavrovskiĭ V A
Biull Eksp Biol Med. 1988 Mar;105(3):322-4.
Sarcoma was induced in C57BL/6 mice with 20-methylcholanthrene. The sarcoma cells were found to be heterogeneous in their transplantability. The study of 9 clones distinct in this property has shown that heterogeneous transplantability was due to different susceptibility to lytic action of macrophages.
用20-甲基胆蒽在C57BL/6小鼠中诱发肉瘤。发现肉瘤细胞在移植性方面具有异质性。对9个在该特性上不同的克隆进行的研究表明,移植性异质性是由于对巨噬细胞溶解作用的敏感性不同所致。