Pelli B, Sturaro A, Traldi P, Lapolla A, Poli T, Fedele D, Crepaldi G
CNR, Area di Ricerca, Padova, Italy.
Biomed Environ Mass Spectrom. 1988 Jan 1;15(1):7-11. doi: 10.1002/bms.1200150103.
The direct determination of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI), present in the acid hydrolysis products of B-poly(L-lysine) and B-albumin and which appears to be a key intermediate in the physicochemical changes occurring during the incubation of protein with glucose, has been carried out by collisional spectroscopy, using a commercial double-focusing, reverse-geometry mass spectrometer and without any sample derivatization and chromatographic separation procedures.
已通过碰撞光谱法，使用商用双聚焦反几何质谱仪，在不进行任何样品衍生化和色谱分离程序的情况下，直接测定了存在于β-聚（L-赖氨酸）和β-白蛋白酸水解产物中的2-（2-呋喃甲酰基）-4（5）-（2-呋喃基）-1H-咪唑（FFI），它似乎是蛋白质与葡萄糖孵育过程中发生的物理化学变化的关键中间体。
