碰撞光谱法作为一种筛选程序，用于测定β-聚（L-赖氨酸）和β-白蛋白酸水解产物中的2-（2-呋喃甲酰基）-4（5）-（2-呋喃基）-1H-咪唑。

Collisional spectroscopy as a screening procedure for the determination of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole from acid hydrolysis of B-poly(L-lysine) and B-albumin.

作者信息

Pelli B, Sturaro A, Traldi P, Lapolla A, Poli T, Fedele D, Crepaldi G

机构信息

CNR, Area di Ricerca, Padova, Italy.

出版信息

Biomed Environ Mass Spectrom. 1988 Jan 1;15(1):7-11. doi: 10.1002/bms.1200150103.

DOI:10.1002/bms.1200150103

Abstract

The direct determination of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI), present in the acid hydrolysis products of B-poly(L-lysine) and B-albumin and which appears to be a key intermediate in the physicochemical changes occurring during the incubation of protein with glucose, has been carried out by collisional spectroscopy, using a commercial double-focusing, reverse-geometry mass spectrometer and without any sample derivatization and chromatographic separation procedures.

摘要

已通过碰撞光谱法，使用商用双聚焦反几何质谱仪，在不进行任何样品衍生化和色谱分离程序的情况下，直接测定了存在于β-聚（L-赖氨酸）和β-白蛋白酸水解产物中的2-（2-呋喃甲酰基）-4（5）-（2-呋喃基）-1H-咪唑（FFI），它似乎是蛋白质与葡萄糖孵育过程中发生的物理化学变化的关键中间体。

相似文献

1

Collisional spectroscopy as a screening procedure for the determination of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole from acid hydrolysis of B-poly(L-lysine) and B-albumin.碰撞光谱法作为一种筛选程序，用于测定β-聚（L-赖氨酸）和β-白蛋白酸水解产物中的2-（2-呋喃甲酰基）-4（5）-（2-呋喃基）-1H-咪唑。

Biomed Environ Mass Spectrom. 1988 Jan 1;15(1):7-11. doi: 10.1002/bms.1200150103.

2

Collisional spectroscopy as a screening procedure for the determination of FFI in complex natural matrices.碰撞光谱法作为测定复杂天然基质中FFI的筛选程序。

J Diabet Complications. 1988 Jan-Mar;2(1):25-6. doi: 10.1016/0891-6632(88)90023-2.

3

Evidence of acid hydrolysis as responsible for 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) production.酸水解是导致2-(2-呋喃甲酰基)-4(5)-(2-呋喃基)-1H-咪唑（FFI）产生的证据。

Clin Chim Acta. 1990 Aug 31;189(3):335-40. doi: 10.1016/0009-8981(90)90315-j.

4

[The development of radioimmunoassay and studies of removal system for advanced glycosylation endproduct].[放射免疫测定法的发展及晚期糖基化终产物清除系统的研究]

Hokkaido Igaku Zasshi. 1990 Mar;65(2):152-60.

5

Mass spectrometry in the study of advanced glycation processes, responsible for long-term diabetes complications.质谱分析法在晚期糖基化过程研究中的应用，该过程与糖尿病长期并发症相关。

Rapid Commun Mass Spectrom. 1991 Nov;5(11):527-33. doi: 10.1002/rcm.1290051109.

6

Detection of an advanced glycosylation product bound to protein in situ.原位检测与蛋白质结合的晚期糖基化产物。

J Biol Chem. 1985 Jul 5;260(13):7970-4.

7

Mechanism of formation of the putative advanced glycosylation end product and protein cross-link 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole.假定的晚期糖基化终产物和蛋白质交联物2-(2-呋喃甲酰基)-4(5)-(2-呋喃基)-1H-咪唑的形成机制。

J Biol Chem. 1988 Aug 5;263(22):10646-52.

8

Non-enzymatic glycation of histones.组蛋白的非酶糖基化

Biol Mass Spectrom. 1993 Feb;22(2):121-3. doi: 10.1002/bms.1200220204.

9

Evidence against in vivo presence of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole, a major fluorescent advanced end product generated by nonenzymatic glycosylation.反对2-(2-呋喃甲酰基)-4(5)-(2-呋喃基)-1H-咪唑（一种由非酶糖基化产生的主要荧光晚期终产物）在体内存在的证据。

J Biol Chem. 1988 Dec 15;263(35):18821-6.

10

Aging of proteins: isolation and identification of a fluorescent chromophore from the reaction of polypeptides with glucose.蛋白质老化：从多肽与葡萄糖反应产物中分离并鉴定一种荧光发色团。

Proc Natl Acad Sci U S A. 1984 May;81(9):2684-8. doi: 10.1073/pnas.81.9.2684.

引用本文的文献

1

Studies on advanced glycation end products by recent mass spectrometric techniques.近年质谱技术在糖基化终末产物研究中的应用

Amino Acids. 1994 Feb;6(1):65-96. doi: 10.1007/BF00808124.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。