2018 年美国性传播导致的新发和现患 HIV 感染情况。

Incident and Prevalent HIV Infections Attributed to Sexual Transmission in the United States, 2018.

机构信息

From the Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA.

出版信息

Sex Transm Dis. 2021 Apr 1;48(4):285-291. doi: 10.1097/OLQ.0000000000001354.

Abstract

BACKGROUND

The Ending the HIV Epidemic: A Plan for America initiative aims to reduce new infections by 2030. Routine assessment of incident and prevalent HIV by transmission risk is essential for monitoring the impact of national, state, and local efforts to end the HIV epidemic.

METHODS

Data reported to the National HIV Surveillance System were used to estimate numbers of incident and prevalent HIV infection attributed to sexual transmission in the United States in 2018. The first CD4 result after diagnosis and a CD4 depletion model were used to generate estimates by transmission category, sex at birth, age group, and race/ethnicity.

RESULTS

In 2018, there were an estimated 32,600 (50% confidence interval [CI], 31,800-33,400) incident and 984,000 (50% CI, 977,000-990,900) prevalent HIV infections attributed to sexual transmission in the United States. Male-to-male sexual contact comprised 74.8% and 69.1% of incident and prevalent HIV infections, respectively. Persons aged 25 to 34 years comprised 39.6% (12,900; 50% CI, 12,400-13,400) of incident infections; however, the number of prevalent infections was highest among persons 55 years and older (29.3%; 288,300 [50% CI, 285,600-291,000]). There were racial/ethnic differences in numbers of incident and prevalent infections among both men who have sex with men and persons with HIV attributable to heterosexual contact.

CONCLUSIONS

In 2018, most incident sexually transmitted HIV infections occurred in men who have sex with men, and the burden was disproportionate for persons aged 24 to 35 years, and Black/African American and Hispanic/Latino adults and adolescents. Efforts to increase the use of effective biomedical and behavioral prevention methods must be intensified to reach the goal to end the HIV epidemic in the United States.

摘要

背景

“终结艾滋病毒流行:美国计划”旨在到 2030 年减少新的艾滋病毒感染。常规评估通过传播途径发现的新发病例和现患艾滋病毒,对于监测国家、州和地方终结艾滋病毒流行的努力的影响至关重要。

方法

使用向国家艾滋病毒监测系统报告的数据,估计 2018 年美国性传播艾滋病毒新发和现患感染人数。使用首次诊断后的 CD4 检测结果和 CD4 细胞消耗模型,按传播类别、出生性别、年龄组和种族/族裔生成估计数。

结果

2018 年,美国估计有 32600 例(50%可信区间[CI],31800-33400)新发和 984000 例(50%CI,977000-990900)性传播艾滋病毒现患感染归因于性传播。男男性接触占新发和现患艾滋病毒感染的 74.8%和 69.1%,分别。25 至 34 岁的人占新发感染的 39.6%(12900 例;50%CI,12400-13400);然而,55 岁及以上的人现患感染人数最多(29.3%;288300[50%CI,285600-291000])。男男性接触者和异性性接触艾滋病毒感染者中,新发和现患感染人数存在种族/族裔差异。

结论

2018 年,大多数新发的性传播艾滋病毒感染发生在男男性接触者中,24 至 35 岁的人以及黑人和西班牙裔成年人和青少年的负担不成比例。必须加强努力,增加有效生物医学和行为预防方法的使用,以实现在美国终结艾滋病毒流行的目标。

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