Department of Public Administration and Policy, Rockefeller College of Public Affairs and Policy, University at Albany, Albany, New York, United States of America.
Center for Collaborative HIV Research in Practice and Policy, School of Public Health, University at Albany, Albany, New York, United States of America.
PLoS One. 2021 Sep 20;16(9):e0257583. doi: 10.1371/journal.pone.0257583. eCollection 2021.
Despite declining HIV infection rates, persistent racial and ethnic disparities remain. Appropriate calculations of diagnosis rates by HIV transmission category, race and ethnicity, and geography are needed to monitor progress towards reducing systematic disparities in health outcomes. We estimated the number of heterosexually active adults (HAAs) by sex and state to calculate appropriate HIV diagnosis rates and disparity measures within subnational regions.
The analysis included all HIV diagnoses attributed to heterosexual transmission in 2018 in the United States, in 50 states and the District of Columbia. Logistic regression models estimated the probability of past-year heterosexual activity among adults in three national health surveys, by sex, age group, race and ethnicity, education category, and marital status. Model-based probabilities were applied to estimated counts of HAAs by state, which were synthesized through meta-analysis. HIV diagnoses were overlaid to calculate racial- and ethnic-specific rates, rate differences (RDs), and rate ratios (RRs) among HAAs by sex and state.
Nationally, HAA women have a two-fold higher HIV diagnosis rate than HAA men (rate per 100,000 HAAs, women: 6.57; men: 3.09). Compared to White non-Hispanic HAAs, Black HAAs have a 20-fold higher HIV diagnosis rate (RR, men: 21.28, women: 19.55; RD, men: 15.40, women: 31.78) and Hispanic HAAs have a 4-fold higher HIV diagnosis rate (RR, men: 4.68, RD, women: 4.15; RD, men: 2.79, RD, women: 5.39). Disparities were ubiquitous across regions, with >75% of states in each region having Black-to-White RR ≥10.
The racial and ethnic disparities across regions suggests a system-wide failure particularly with respect to preventing HIV among Black and Hispanic women. Pervasive disparities emphasize the role for coordinated federal responses such as the current Ending the HIV Epidemic (EHE) initiative.
尽管艾滋病毒感染率有所下降,但仍存在持续的种族和族裔差异。需要按艾滋病毒传播类别、种族和族裔以及地理位置适当计算诊断率,以监测在减少健康结果方面存在的系统性差异方面取得的进展。我们估计了按性别和州划分的异性恋活跃成年人(HAA)数量,以计算次国家级地区内适当的艾滋病毒诊断率和差异衡量标准。
该分析包括美国 2018 年所有归因于异性传播的艾滋病毒诊断,涉及 50 个州和哥伦比亚特区。通过性别、年龄组、种族和族裔、教育程度和婚姻状况,对三项全国健康调查中成年人过去一年异性活动的可能性进行逻辑回归模型估计。基于模型的概率适用于按州划分的 HAA 估计数,通过荟萃分析进行综合。将艾滋病毒诊断叠加起来,以计算按性别和州划分的 HAA 的特定种族和族裔的比率、比率差异(RD)和比率比(RR)。
在全国范围内,HAA 女性的艾滋病毒诊断率是 HAA 男性的两倍(每 10 万 HAA 中的诊断率,女性:6.57;男性:3.09)。与白人非西班牙裔 HAA 相比,黑人 HAA 的艾滋病毒诊断率高 20 倍(RR,男性:21.28,女性:19.55;RD,男性:15.40,女性:31.78),西班牙裔 HAA 的艾滋病毒诊断率高 4 倍(RR,男性:4.68,RD,女性:4.15;RD,男性:2.79,RD,女性:5.39)。各地都存在着普遍的差异,每个地区超过 75%的州的黑人与白人的 RR 都≥10。
各地的种族和族裔差异表明系统存在全面失败,特别是在预防黑人和西班牙裔女性中的艾滋病毒方面。普遍存在的差异强调了协调联邦应对措施的作用,例如当前的终结艾滋病毒流行倡议。