急性小脑共济失调和肌阵挛伴或不伴眼球震颤：与 COVID-19 相关的拟传染性综合征。

Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.

机构信息

Assistance Publique-Hôpitaux de Paris, Service de Neurologie, Hôpital Pitié-Salpêtrière, Paris, France.

Service de Neurologie, Centre Hospitalier Universitaire de la Guadeloupe, Pointe-à-Pitre, France.

出版信息

Eur J Neurol. 2021 Oct;28(10):3533-3536. doi: 10.1111/ene.14726.

DOI:10.1111/ene.14726

PMID:33492711

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8013847/

Abstract

BACKGROUND AND PURPOSE

Patients with COVID-19 can have central or peripheral neurological manifestations.

METHODS

The cases of two patients with acute cerebellar ataxia and myoclonus associated with COVID-19 are reported (with Video S1) and five previously reported patients are discussed.

RESULTS

Acute cerebellar ataxia and myoclonus started between 10 days and 6 weeks after the first manifestations of COVID-19. Opsoclonus or ocular flutter was present in four patients. Patients were treated with intravenous immunoglobulins and/or steroids except for one patient, resulting in a striking improvement within a week.

CONCLUSION

Acute cerebellar ataxia and myoclonus with or without opsoclonus belongs to the wide spectrum of neurological manifestations associated with COVID-19. It is important to recognize this possible manifestation since early treatment allows for rapid recovery.

摘要

背景与目的

COVID-19 患者可出现中枢或周围神经系统表现。

方法

报告了两例与 COVID-19 相关的急性小脑性共济失调和肌阵挛病例（附视频 S1），并讨论了另外 5 例先前报道的病例。

结果

急性小脑性共济失调和肌阵挛在 COVID-19 首发症状后 10 天至 6 周内出现。4 例患者存在眼球震颤或眼球扑动。除了 1 例患者外，其余患者均接受了静脉注射免疫球蛋白和/或类固醇治疗，结果在一周内显著改善。

结论

伴有或不伴有眼球震颤的急性小脑性共济失调和肌阵挛属于 COVID-19 相关的广泛神经系统表现之一。认识到这种可能的表现很重要，因为早期治疗可实现快速康复。

相似文献

Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.

Eur J Neurol. 2021 Oct;28(10):3533-3536. doi: 10.1111/ene.14726.

Postinfectious SARS-CoV-2 Opsoclonus-Myoclonus-Ataxia Syndrome.

J Neuroophthalmol. 2022 Jun 1;42(2):251-255. doi: 10.1097/WNO.0000000000001498. Epub 2021 Dec 30.

Neurol Neurochir Pol. 2021;55(3):310-313. doi: 10.5603/PJNNS.a2021.0036. Epub 2021 Jun 7.

Opsoclonus myoclonus ataxia syndrome in severe acute respiratory syndrome coronavirus-2.

J Neurovirol. 2021 Jun;27(3):501-503. doi: 10.1007/s13365-021-00974-0. Epub 2021 Mar 31.

Opsoclonus-Myoclonus-Ataxia Syndrome (OMAS) Associated with SARS-CoV-2 Infection: Post-Infectious Neurological Complication with Benign Prognosis.

Tremor Other Hyperkinet Mov (N Y). 2021 Feb 10;11:7. doi: 10.5334/tohm.580.

Myoclonus status revealing COVID 19 infection.

Seizure. 2023 Jan;104:12-14. doi: 10.1016/j.seizure.2022.11.010. Epub 2022 Nov 22.

Myoclonus and cerebellar ataxia associated with COVID-19: a case report and systematic review.

J Neurol. 2021 Oct;268(10):3517-3548. doi: 10.1007/s00415-021-10458-0. Epub 2021 Feb 22.

Retrospective analysis of COVID-19 patients with Guillain-Barre, Miller-Fisher, and opsoclonus-myoclonus-ataxia syndromes-a case series.

Wien Med Wochenschr. 2024 Feb;174(1-2):30-34. doi: 10.1007/s10354-023-01018-4. Epub 2023 Jul 31.

Clinical heterogeneity in patients with myoclonus associated to COVID-19.

Neurol Sci. 2022 Mar;43(3):1587-1592. doi: 10.1007/s10072-021-05802-1. Epub 2022 Jan 6.

Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature.

J Neurovirol. 2021 Feb;27(1):26-34. doi: 10.1007/s13365-020-00941-1. Epub 2021 Jan 25.

引用本文的文献

A case of suspected autoimmune encephalopathy with involuntary movements and cognitive dysfunction post-COVID-19.

PCN Rep. 2024 Jul 15;3(3):e224. doi: 10.1002/pcn5.224. eCollection 2024 Sep.

Clinical and diagnostic features of long-COVID patients presenting with neurologic symptoms in Chicago.

J Neural Transm (Vienna). 2024 Aug;131(8):961-969. doi: 10.1007/s00702-024-02789-9. Epub 2024 Jun 7.

Characterisation of internal tremors and vibration symptoms.

BMJ Open. 2023 Dec 28;13(12):e077389. doi: 10.1136/bmjopen-2023-077389.

Ocular Flutter-Myoclonus-Ataxia Syndrome After mRNA BNT162b2 COVID-19 Vaccine: A Case Report.

Noro Psikiyatr Ars. 2023 Nov 16;60(4):376-379. doi: 10.29399/npa.28205. eCollection 2023.

De Novo Movement Disorders Associated with COVID-19- A Systematic Review of Individual Patients.

Ann Indian Acad Neurol. 2023 Sep-Oct;26(5):702-707. doi: 10.4103/aian.aian_572_23. Epub 2023 Oct 18.

Opsoclonus-Myoclonus-Ataxia Syndrome Due to Covid-19.

Cerebellum. 2024 Jun;23(3):1245-1248. doi: 10.1007/s12311-023-01610-9. Epub 2023 Oct 9.

Movement Disorders and SARS-CoV-2.

Mov Disord Clin Pract. 2022 Dec 7;10(Suppl 2):S9-S17. doi: 10.1002/mdc3.13615. eCollection 2023 Aug.

Cerebrospinal Fluid Anti-Neuronal Autoantibodies in COVID-19-Associated Limbic Encephalitis with Acute Cerebellar Ataxia and Myoclonus Syndrome: Case Report and Literature Review.

Diagnostics (Basel). 2023 Jun 14;13(12):2055. doi: 10.3390/diagnostics13122055.

Opsoclonus Myoclonus Ataxia Syndrome Due to SARS-CoV-2.

Neuroophthalmology. 2022 Dec 15;47(1):1-6. doi: 10.1080/01658107.2022.2128378. eCollection 2023.

Post COVID Acute Cerebellar Ataxia and Myoclonus (ACAM).

Ann Indian Acad Neurol. 2022 Sep-Oct;25(5):948-950. doi: 10.4103/aian.aian_187_22. Epub 2022 Oct 31.

本文引用的文献

Reversible Myoclonus-Ataxia as a Postinfectious Manifestation of COVID-19.

Mov Disord Clin Pract. 2020 Sep 28;7(8):977-979. doi: 10.1002/mdc3.13088. eCollection 2020 Nov.

Opsoclonus Myoclonus Ataxia Syndrome in the Setting of COVID-19 Infection.

Neurology. 2021 Jan 5;96(1):33. doi: 10.1212/WNL.0000000000010978. Epub 2020 Oct 1.

Opsoclonus-Myoclonus-Ataxia Syndrome Related to the Novel Coronavirus (COVID-19).

J Neuroophthalmol. 2021 Sep 1;41(3):e288-e289. doi: 10.1097/WNO.0000000000001129.

Myoclonus and Cerebellar Ataxia Following COVID-19.

Mov Disord Clin Pract. 2020 Sep 28;7(8):974-976. doi: 10.1002/mdc3.13049. eCollection 2020 Nov.

Autoimmune Encephalitis Concomitant with SARS-CoV-2 Infection: Insight from F-FDG PET Imaging and Neuronal Autoantibodies.

J Nucl Med. 2020 Dec;61(12):1726-1729. doi: 10.2967/jnumed.120.249292. Epub 2020 Jul 24.

Neurological associations of COVID-19.

Lancet Neurol. 2020 Sep;19(9):767-783. doi: 10.1016/S1474-4422(20)30221-0. Epub 2020 Jul 2.

Update on opsoclonus-myoclonus syndrome in adults.

J Neurol. 2019 Jun;266(6):1541-1548. doi: 10.1007/s00415-018-9138-7. Epub 2018 Nov 27.

Principles and approaches to the treatment of immune-mediated movement disorders.

Eur J Paediatr Neurol. 2018 Mar;22(2):292-300. doi: 10.1016/j.ejpn.2017.11.010. Epub 2017 Dec 19.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

急性小脑共济失调和肌阵挛伴或不伴眼球震颤：与 COVID-19 相关的拟传染性综合征。

Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.

机构信息

Assistance Publique-Hôpitaux de Paris, Service de Neurologie, Hôpital Pitié-Salpêtrière, Paris, France.

Service de Neurologie, Centre Hospitalier Universitaire de la Guadeloupe, Pointe-à-Pitre, France.

出版信息

Eur J Neurol. 2021 Oct;28(10):3533-3536. doi: 10.1111/ene.14726.

DOI:10.1111/ene.14726

PMID:33492711

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8013847/

Abstract

BACKGROUND AND PURPOSE

Patients with COVID-19 can have central or peripheral neurological manifestations.

METHODS

The cases of two patients with acute cerebellar ataxia and myoclonus associated with COVID-19 are reported (with Video S1) and five previously reported patients are discussed.

RESULTS

CONCLUSION

摘要

背景与目的

COVID-19 患者可出现中枢或周围神经系统表现。

方法

报告了两例与 COVID-19 相关的急性小脑性共济失调和肌阵挛病例（附视频 S1），并讨论了另外 5 例先前报道的病例。

急性小脑共济失调和肌阵挛伴或不伴眼球震颤：与 COVID-19 相关的拟传染性综合征。

Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.

机构信息

出版信息

BACKGROUND AND PURPOSE

METHODS

RESULTS

CONCLUSION

背景与目的

方法

结果

结论

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

急性小脑共济失调和肌阵挛伴或不伴眼球震颤：与 COVID-19 相关的拟传染性综合征。

Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.

机构信息

出版信息

BACKGROUND AND PURPOSE

METHODS

RESULTS

CONCLUSION

背景与目的

方法

结果

结论