Dekens J, Lepointe F, Besserve P, Fournier T, Lephay A, Ossart M
Département d'Anesthésie-Réanimation B, C.H.R.U., Amiens.
Cah Anesthesiol. 1988 Jan-Feb;36(1):25-7.
Post operative pain is a constant and deleterious factor, resulting from surgical traumatism of the operated tissues; this aggression leads to a local inflammatory and painful reaction mediated by prostaglandins. Non steroid anti-inflammatory drugs inhibit their synthesis. In this study, ketoprofene appears to be an interesting treatment of post operative pain especially in orthopedic and traumatologic surgery.
术后疼痛是一个持续且有害的因素，由手术对手术部位组织造成的创伤引起；这种侵害会引发由前列腺素介导的局部炎症和疼痛反应。非甾体类抗炎药会抑制它们的合成。在本研究中，酮洛芬似乎是术后疼痛的一种有效治疗方法，尤其在骨科和创伤外科手术中。
