Vathana P, Pakpianpairoj C, Prasartritha T
Institute of Orthopaedics, Lerdsin Hospital, Bangkok, Thailand.
J Med Assoc Thai. 1998 Apr;81(4):283-7.
A prospective, open label, randomized study to compare efficacy of intramuscular administration of ketoprofen and morphine for post operative analgesia in elective orthopaedic surgery was performed in 50 patients. The procedures were open reduction and internal fixation of long bone fractures (26 cases), hip replacement (9 cases) and spinal surgery (15 cases). Pain intensity and pain relief in both groups were evaluated at 1, 3 and 6 hours post-injection. There was no significant differences in pain relief of both groups (P = 0.05). The side effects of intramuscular ketoprofen were encountered in only 8 per cent. Ketoprofen injection is an alternative for post operative pain relief.
对50例择期骨科手术患者进行了一项前瞻性、开放标签、随机研究，以比较肌肉注射酮洛芬和吗啡用于术后镇痛的疗效。手术包括长骨骨折切开复位内固定术（26例）、髋关节置换术（9例）和脊柱手术（15例）。在注射后1、3和6小时评估两组的疼痛强度和疼痛缓解情况。两组的疼痛缓解情况无显著差异（P = 0.05）。肌肉注射酮洛芬的副作用仅在8%的患者中出现。酮洛芬注射液是术后缓解疼痛的一种替代方法。
