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印度护肤品中的汞及其消费者暴露风险。

Mercury in skin-care products in India and consumer exposure risks.

机构信息

Department of Civil Engineering, Indian Institute of Technology (IIT) Hyderabad, Kandi, TS, 502285, India.

Department of Civil Engineering, Indian Institute of Technology (IIT) Hyderabad, Kandi, TS, 502285, India.

出版信息

Regul Toxicol Pharmacol. 2021 Apr;121:104870. doi: 10.1016/j.yrtph.2021.104870. Epub 2021 Jan 22.

Abstract

We report concentrations of mercury in skin-care products in India and the associated health risks. Mercury concentrations were 0.11 μg/kg (median; 5th percentile-95th percentile = 0.04-0.58 μg/kg; n = 24) in body lotions, 0.22 μg/kg (0.04-0.38 μg/kg, n = 10) in moisturizing lotions, 0.67 μg/kg (0.30-1.33 μg/kg, n = 8) in blemish balms, 0.16 μg/kg (0.06-7.43 μg/kg, n = 11) in bleaches, 0.13 μg/kg (0.04-0.98 μg/kg, n = 34) in skin lightning (fairness) creams manufactured within the country, and 9.24 × 10 μg/kg (2.92 × 10-3.17 × 10 μg/kg, n = 14) in imported skin lightning (fairness) creams, much higher than the 1 ppm (1 ppm = 10 μg/kg) regulatory limit. Probabilistic human health risk assessment for adult women (age > 21 y) revealed that computed hazard quotients from dermal exposure to the high-mercury fairness creams were >100 in all cases. The mass of mercury entering into the society via skin-care products is highly sensitive to the mass of high-mercury fairness creams that is imported to India; ten tonnes of import can introduce 29-317 kg of mercury every year. As such, analysis and labeling of mercury contents in skin-care products by manufacturers, and raising awareness among regulatory authorities to restrict the import of high-mercury fairness creams, is required.

摘要

我们报告了印度护肤品中的汞浓度及其相关健康风险。汞浓度如下:身体乳液中为 0.11μg/kg(中位数;5 百分位数-95 百分位数=0.04-0.58μg/kg;n=24),保湿乳液中为 0.22μg/kg(0.04-0.38μg/kg,n=10),祛斑霜中为 0.67μg/kg(0.30-1.33μg/kg,n=8),漂白剂中为 0.16μg/kg(0.06-7.43μg/kg,n=11),国内生产的皮肤美白(增亮)霜中为 0.13μg/kg(0.04-0.98μg/kg,n=34),进口皮肤美白(增亮)霜中为 9.24×10μg/kg(2.92×10-3.17×10μg/kg,n=14),远高于 1ppm(1ppm=10μg/kg)的监管限值。对成年女性(年龄>21 岁)进行的概率性人类健康风险评估显示,所有情况下,通过皮肤接触高汞美白霜而产生的计算危害系数均>100。通过护肤品进入社会的汞质量对印度进口高汞美白霜的质量高度敏感;十吨进口量每年可引入 29-317 公斤汞。因此,制造商需要对护肤品中的汞含量进行分析和标注,并提高监管机构的认识,以限制高汞美白霜的进口。

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