Grupo de Bioquímica Vegetal, Instituto de Biología Agrícola de Mendoza (IBAM), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-Universidad Nacional de Cuyo (UNCuyo), Almirante Brown 500, M5528AHB Chacras de Coria, Argentina.
Laboratorio de Cromatografía para Agroalimentos, IBAM-CONICET-UNCuyo, Almirante Brown 500, M5528AHB Chacras de Coria, Argentina.
Food Chem. 2021 Jun 30;348:129063. doi: 10.1016/j.foodchem.2021.129063. Epub 2021 Jan 14.
Grapevine woody by-products contain bioactive substances, mainly phenolic compounds (PCs), whose beneficial health effects initially depends on their levels of intake and bioavailability. Therefore, in-vitro simulated gastrointestinal digestion (GID; oral, gastric and intestinal phases) was performed to evaluate the bioaccessibility and antioxidant capacity (AC) of PCs extracts recovered from grapevine bunch stem and cane from Malbec grape cultivar. The total PCs in cane and bunch stem extracts were 74 and 20% bioaccessible, respectively. Syringic acid, cinnamic acid, ε-viniferin, naringenin and myricetin were highly bioaccessible, noticeably ε-viniferin in cane extract with 137%. The high bioaccessibility observed, particularly for compounds at high concentration such as ε-viniferin, will help to better understand the bioactive potential of these by-products. In this sense, bunch stems and canes can be considered as new and sustainable sources of bioactive substances for applications as functional ingredients or nutraceuticals in food and pharmaceutical industries.
葡萄木质副产物含有生物活性物质，主要是酚类化合物（PCs），其对健康的有益影响最初取决于其摄入量和生物利用度。因此，进行了体外模拟胃肠道消化（GID；口腔、胃和肠道阶段），以评估从马尔贝克葡萄品种的葡萄串茎和葡萄藤中回收的 PCs 提取物的生物可及性和抗氧化能力（AC）。藤本和串茎提取物中的总 PCs 分别有 74%和 20%是生物可及的。丁香酸、肉桂酸、ε-白藜芦醇、柚皮素和杨梅素具有很高的生物可及性，尤其是藤本提取物中的 ε-白藜芦醇，可达 137%。观察到的高生物可及性，特别是对于高浓度化合物如 ε-白藜芦醇，将有助于更好地理解这些副产物的生物活性潜力。从这个意义上说，葡萄串茎和葡萄藤可以被视为功能性成分或营养保健品在食品和制药行业应用的生物活性物质的新的和可持续来源。
