Department of Otorhinolaryngology, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
J Laryngol Otol. 2021 Feb;135(2):142-146. doi: 10.1017/S0022215120002492. Epub 2021 Jan 26.
Laryngopharyngeal reflux symptoms assessed with the reflux symptom index can overlap with non-allergic rhinitis symptoms. This study aims to explore the association between the reflux symptom index and nasal symptoms in non-allergic rhinitis patients.
A cross-sectional study was conducted on consecutive adults with non-allergic rhinitis. The reflux symptom index (score of more than 13 = laryngopharyngeal reflux) and nasal symptoms (categorised as mild (total score of 0-3), moderate (4-7) or severe (8-12)) were assessed.
The study included 227 participants (aged 58.64 ± 12.39 years, 59.5 per cent female). The reflux symptom index scores increased with total nasal symptom scores (mild vs moderate vs severe, 8.61 ± 6.27 vs 12.94 ± 7.4 vs 16.40 ± 8.10; p < 0.01). Logistic regression indicated that laryngopharyngeal reflux is more likely in patients with severe nose block (odds ratio 5.47 (95 per cent confidence interval = 2.16-13.87); p < 0.01).
Laryngopharyngeal reflux symptoms are associated with nasal symptom severity, and nasal symptoms should be primarily treated. Those with predominant nose block and laryngopharyngeal reflux symptoms are more likely to have laryngopharyngeal reflux.
通过反流症状指数评估的咽喉反流症状与非变应性鼻炎症状可能存在重叠。本研究旨在探讨非变应性鼻炎患者的反流症状指数与鼻部症状之间的关系。
对连续的非变应性鼻炎成人患者进行了横断面研究。评估了反流症状指数（评分>13=咽喉反流）和鼻部症状（分为轻度（总分 0-3）、中度（4-7）或重度（8-12））。
该研究纳入了 227 名参与者（年龄 58.64±12.39 岁，59.5%为女性）。反流症状指数评分随总鼻部症状评分的增加而升高（轻度 vs 中度 vs 重度，8.61±6.27 vs 12.94±7.4 vs 16.40±8.10；p<0.01）。Logistic 回归分析表明，严重鼻塞的患者发生咽喉反流的可能性更大（比值比 5.47（95%置信区间=2.16-13.87）；p<0.01）。
咽喉反流症状与鼻部症状严重程度相关，应首先治疗鼻部症状。那些以鼻塞为主且伴有咽喉反流症状的患者更有可能发生咽喉反流。
