Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Medical University of South Carolina, Shawn Jenkins Children's Hospital, 10 McClennan Banks Drive, MSC 915, Charleston, SC 29425, United States.
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Uniformed Services University, United States.
Semin Perinatol. 2021 Mar;45(2):151384. doi: 10.1016/j.semperi.2020.151384. Epub 2021 Jan 2.
This review highlights clinical outcomes of human milk from infancy through adulthood. Human milk outcomes of both preterm and term infants, including critically ill term infants (such as infants with congenital heart disease and those requiring therapeutic hypothermia) are summarized. Several human milk diets are identified to reduce the risk of specific diseases. Emerging research of newly discovered components of human milk are also reviewed. Human milk has significant effects on the gut microbiome, somatic growth, and neurocognitive outcomes. Continued research promises to improve donor human milk and donor milk derived products to achieve better outcomes for infants who do not receive their own mother's milk. The promotion of human milk is well-founded on evidence from the previous half century.
本综述重点介绍了人乳在婴儿期到成年期的临床效果。总结了早产儿和足月儿(如患有先天性心脏病和需要治疗性低温的婴儿)的人乳效果。确定了几种人乳饮食来降低特定疾病的风险。还回顾了新发现的人乳成分的新兴研究。人乳对肠道微生物组、躯体生长和神经认知结果有重要影响。持续的研究有望改善捐赠人乳和人乳衍生产品,以实现那些未接受其母亲人乳的婴儿的更好结果。人乳的推广有过去半个世纪的证据支持。