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在干预研究中招募参与者:挑战与解决方案。

Recruiting in intervention studies: challenges and solutions.

机构信息

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

出版信息

BMJ Open. 2021 Jan 25;11(1):e044702. doi: 10.1136/bmjopen-2020-044702.

Abstract

INTRODUCTION

In order for study results to be relevant for practice, the study participants should represent the source population. A common problem is recruitment of sufficient and representative subjects, threatening the external validity of the study and, ultimately, evidence-based practice. The aim was to highlight common challenges and to present possible solutions to recruitment.

METHODS

Using four recent randomised controlled trials as examples, common recruitment challenges were highlighted and solutions were proposed. The four studies represented some common and some specific challenges, but they investigated interventions for the prevention of the two major public health challenges of today: musculoskeletal pain and common mental disorders.

RESULTS

Identified challenges and suggested solutions were presented as a checklist to be used for future trials in order to aid recruitment and reporting thereof.

摘要

简介

为了使研究结果与实践相关,研究参与者应代表源人群。一个常见的问题是招募足够和有代表性的受试者,这威胁到研究的外部有效性,最终也威胁到循证实践。目的是强调常见的挑战,并提出可能的解决方案。

方法

使用四个最近的随机对照试验作为例子,突出了常见的招募挑战,并提出了解决方案。这四项研究代表了一些常见的和一些具体的挑战,但它们调查了预防当今两个主要公共卫生挑战的干预措施:肌肉骨骼疼痛和常见的精神障碍。

结果

确定的挑战和建议的解决方案以检查表的形式呈现,以便用于未来的试验,以帮助招募和报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3705/7839899/c201ea903918/bmjopen-2020-044702f01.jpg

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