Heinig J H, Engel T, Weeke E R
Allergy Clinic and Medical Department, County Hospital, Roskilde, Denmark.
Clin Allergy. 1988 Jan;18(1):71-8. doi: 10.1111/j.1365-2222.1988.tb02845.x.
Sixty-three patients, applying to the casualty ward after a bee or wasp sting, were tested. On the day of admission, and 4 weeks later, blood was sampled to measure specific IgE and IgG against bee and wasp venom and total IgE. Four weeks after the insect sting, all patients were examined with skin-prick test (1, 10 and 100 micrograms/ml), and intracutaneous test (0.05 ml of extract 1.0 microgram/ml). The amount of venom-specific IgE and IgG increased significantly during the 4-week period, venom-specific IgE was most pronounced in patients experiencing the most severe clinical reactions. However, no significant correlations were found between the results of the immunological tests carried out 4 weeks after the insect sting and the clinical reaction upon the insect sting.
对63名在被蜜蜂或黄蜂蜇伤后前往急诊病房就诊的患者进行了检测。在入院当天以及4周后采集血液样本，以检测针对蜜蜂和黄蜂毒液的特异性IgE和IgG以及总IgE。昆虫蜇伤4周后，所有患者均接受了皮肤点刺试验（1、10和100微克/毫升）和皮内试验（0.05毫升1.0微克/毫升的提取物）。在这4周期间，毒液特异性IgE和IgG的量显著增加，毒液特异性IgE在经历最严重临床反应的患者中最为明显。然而，在昆虫蜇伤4周后进行的免疫测试结果与昆虫蜇伤后的临床反应之间未发现显著相关性。
