Université Paris Saclay, CNRS, Institut de Chimie Moléculaire et des Matériaux d'Orsay, 91405, Orsay, France.
Chem Rec. 2021 Feb;21(2):427-439. doi: 10.1002/tcr.202000166. Epub 2021 Jan 26.
Since the discovery of their extraordinary reactivity in the hydrolytic kinetic resolution of terminal epoxides about twenty years ago, chiral cobalt-salen complexes have been shown to be essential for many other asymmetric catalytic reactions. This account summarizes the inspiring works dedicated to the discovery of their new reactivity and their mode of action, as well as the new processes towards the optimization of their cooperativity for bimetallic activation and the implementation of their effective immobilization, including also our contribution on these topics.
自大约二十年前发现它们在手性钴-salen 配合物在末端环氧化合物的水解动力学拆分中的非凡反应活性以来，它们已被证明对于许多其他不对称催化反应是必不可少的。本文总结了致力于发现它们的新反应性和作用模式的鼓舞人心的工作，以及优化其协同作用以进行双金属活化和实现有效固定化的新方法，包括我们在这些主题上的贡献。
