Department of Radiology, MacKay Memorial Hospital, Taipei, Taiwan, ROC.
Department of Medicine, MacKay Medical College, New Taipei City, Taiwan, ROC.
J Chin Med Assoc. 2021 Mar 1;84(3):273-279. doi: 10.1097/JCMA.0000000000000492.
Aortic dissection is a rare but severe complication of percutaneous transluminal angioplasty and stenting (PTAS) for stenosis of the subclavian artery (SA). This retrospective study was designed to evaluate the risk factors and outcomes of patients with severe stenosis of the SA who underwent PTAS complicated by aortic dissection.
Between 1999 and 2018, 169 cases of severe symptomatic stenosis of the SA underwent PTAS at our institute. Of them, six cases complicated by aortic dissection were included in this study. We evaluated the demographic features, technical factors of PTAS, and clinical outcomes in these six patients.
Aortic dissection occurred in 5.3% (6/113) of all left SA stenting cases but in none of the right SA stenting cases. All patients had hypertension and a high severity of SA stenosis (85.0 ± 13.0%, 60%-95%). Five of the six patients received balloon-expandable stents (83.3%). All patients had spontaneous resolution of the aortic dissection with conservative treatment. In a 63.33 ± 33.07 (7-118) month follow-up, five of the six patients (83.3%) had long-term symptom relief and stent patency.
Aortic dissection occurred in patients who underwent PTAS for severe stenosis of the left SA, mainly with balloon-expandable stents. We suggest using self-expandable stents and angioplasty with an undersized balloon during PTAS for severe stenosis of the left proximal SA to prevent aortic dissection.
经皮腔内血管成形术和支架置入术(PTAS)治疗锁骨下动脉(SA)狭窄是一种罕见但严重的并发症,可导致主动脉夹层。本回顾性研究旨在评估 PTAS 治疗严重 SA 狭窄并发主动脉夹层的患者的危险因素和结局。
1999 年至 2018 年,我院共 169 例严重症状性 SA 狭窄患者接受了 PTAS。其中,6 例并发主动脉夹层,纳入本研究。我们评估了这 6 例患者的人口统计学特征、PTAS 的技术因素和临床结局。
主动脉夹层发生于 5.3%(6/113)的所有左 SA 支架置入病例中,而右 SA 支架置入病例中无一例发生。所有患者均有高血压和严重的 SA 狭窄(85.0±13.0%,60%-95%)。6 例患者中有 5 例接受了球囊扩张支架(83.3%)。所有患者均经保守治疗后主动脉夹层自发缓解。在 63.33±33.07(7-118)个月的随访中,6 例患者中的 5 例(83.3%)有长期症状缓解和支架通畅。
PTAS 治疗左 SA 严重狭窄的患者中发生了主动脉夹层,主要与球囊扩张支架有关。我们建议在 PTAS 治疗左近端 SA 严重狭窄时使用自膨式支架和小号球囊扩张,以预防主动脉夹层。