Suppr超能文献

青少年时期与成年早期开始规律使用大麻:一项 20 年前瞻性队列研究的后期后果。

Young-adult compared to adolescent onset of regular cannabis use: A 20-year prospective cohort study of later consequences.

机构信息

Centre for Youth Substance Abuse Research, The University of Queensland, Brisbane, Australia.

Centre for Adolescent Health, Murdoch Children's Research Institute, Melbourne, Australia.

出版信息

Drug Alcohol Rev. 2021 May;40(4):627-636. doi: 10.1111/dar.13239. Epub 2021 Jan 26.

Abstract

INTRODUCTION

This paper compares consequences of cannabis use initiated after high school with those of cannabis initiation in adolescence, with estimates of the proportion of adverse consequences accounted for by adult-onset and adolescent-onset cannabis users.

METHODS

A state-representative sample in Victoria, Australia (n = 1792) participated in a 10-wave longitudinal study and was followed from age 15 to 35 years. Exposure variable: Patterns of cannabis use across 20 years. Outcomes at age 35: Alcohol use, smoking, illicit drug use, relationship status, financial hardship, depression, anxiety and employment status.

RESULTS

Substantially more participants (13.6%) initiated regular use after high school (young-adult onset) than in adolescence (7.7%, adolescent onset). By the mid-30s, both young-adult and adolescent-onset regular users were more likely than minimal/non-users (63.5%) to have used other illicit drugs (odds ratio [OR] > 20.4), be a high-risk alcohol drinker (OR > 3.7), smoked daily (OR > 7.2) and less likely to be in relationships (OR < 0.4). As the prevalence of the young-adult-onset group was nearly double of the adolescent-onset group, it accounted for a higher proportion of adverse consequences than the adolescent-onset group.

DISCUSSION AND CONCLUSIONS

Cannabis users who began regular use in their teens had poorer later life outcomes than non-using peers. The larger group who began regular cannabis use after leaving high school accounted for most cannabis-related harms in adulthood. Given the legalisation of cannabis use in an increasing number of jurisdictions, we should increasingly expect harms from cannabis use to lie in those commencing use in young adulthood.

摘要

引言

本文比较了高中后开始使用大麻和青少年时期开始使用大麻的后果,并估计了成年和青少年开始使用大麻所导致的不良后果的比例。

方法

澳大利亚维多利亚州的一个具有代表性的州样本(n=1792)参与了一项 10 波的纵向研究,从 15 岁到 35 岁进行了随访。暴露变量:20 年来大麻使用模式。35 岁时的结果:饮酒、吸烟、使用非法药物、关系状况、经济困难、抑郁、焦虑和就业状况。

结果

与青少年时期开始(7.7%,青少年开始)相比,更多的参与者(13.6%)在高中毕业后开始经常使用大麻(青年开始)。到 30 多岁时,与最低/非使用者(63.5%)相比,青年开始和青少年开始的经常使用者更有可能使用其他非法药物(优势比[OR] > 20.4)、是高风险饮酒者(OR > 3.7)、每天吸烟(OR > 7.2),并且更不可能有伴侣(OR < 0.4)。由于青年开始组的患病率几乎是青少年开始组的两倍,因此它比青少年开始组造成了更高比例的不良后果。

讨论与结论

在青少年时期开始经常使用大麻的使用者比不使用大麻的同龄人有更差的晚年生活结果。离开高中后开始经常使用大麻的较大群体在成年后造成了大多数与大麻相关的危害。鉴于越来越多的司法管辖区大麻使用合法化,我们应该越来越多地预期大麻使用的危害会存在于那些开始在成年早期使用大麻的人之中。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验