宿主-微生物相互作用：沉溺于黏液泥沼中。
Host-Microbe Interactions: Wallowing in Mucus Mire.
机构信息
Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55117, USA.
出版信息
Curr Biol. 2021 Jan 25;31(2):R85-R88. doi: 10.1016/j.cub.2020.11.034.
PMID:33497639
Abstract
Mucin glycoproteins confer robust protection against infection by regulating bacterial behavior and virulence gene expression, but the mechanistic bases are poorly understood. New work implicates glycan-based signaling through a carbohydrate-binding sensor kinase in mediating pathogen behavior at the mucosal interface.
摘要
粘蛋白糖蛋白通过调节细菌行为和毒力基因表达提供强大的抗感染保护，但机制基础知之甚少。新的研究表明，通过碳水化合物结合传感器激酶的聚糖信号传导在介导黏膜界面病原体行为中起作用。
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