Kanerva L, Estlander T, Jolanki R
Section of Dermatology, Institute of Occupational Health, Helsinki, Finland.
Contact Dermatitis. 1988 Jan;18(1):10-5. doi: 10.1111/j.1600-0536.1988.tb05482.x.
Data on allergic contact dermatitis from acrylates and 4 patients sensitized during routine patch testing are reported. During 1982-1985, we used 7 different acrylates for tests. 1 patient out of 22 (= 4.5%) was sensitized to ethyl acrylate and butyl acrylate (1% pet.). Since September 1985, we have used a commercial (meth)acrylate series containing 28 substances. 3 of 24 patients tested became sensitized to ethyl acrylate, 2-hydroxyethyl acrylate and 2-hydroxypropyl acrylate (0.5% pet.). Because active sensitization with acrylates can be very harmful, it may be necessary to use lower concentrations than recommended. Currently, we test ethyl acrylate, 2-hydroxyethyl acrylate and 2-hydroxypropyl acrylate at 0.167% pet.
报告了有关丙烯酸酯引起的过敏性接触性皮炎的数据以及4例在常规斑贴试验中致敏的患者。1982年至1985年期间，我们使用7种不同的丙烯酸酯进行试验。22例患者中有1例（=4.5%）对丙烯酸乙酯和丙烯酸丁酯（1%凡士林）致敏。自1985年9月以来，我们使用了一种含有28种物质的商用（甲基）丙烯酸酯系列。24例受试患者中有3例对丙烯酸乙酯、丙烯酸2-羟乙酯和丙烯酸2-羟丙酯（0.5%凡士林）致敏。由于丙烯酸酯的主动致敏可能非常有害，可能有必要使用低于推荐浓度的剂量。目前，我们以0.167%凡士林的浓度对丙烯酸乙酯、丙烯酸2-羟乙酯和丙烯酸2-羟丙酯进行试验。
