Department of Pharmacy, College of Pharmacy, Kangwon National University, 1 Gangwondaehakgil, Chuncheon-si, Gangwon-do 24341, Korea.
Department of Dental Hygiene, College of Health Science, Kangwon National University, 346 Hwangjo-gil, Dogye-up, Samcheok-si, Gangwon-do 25945, Korea.
Int J Environ Res Public Health. 2021 Jan 20;18(3):871. doi: 10.3390/ijerph18030871.
Depression causes damage to the immune defense mechanism, and it can worsen periodontitis due to the accumulation of periodontitis pathogens. This study was conducted in order to explore the association of diagnosed depression and self-reported depression symptom with periodontitis by using the Korean National Health and Nutrition Examination Survey 7th (KNHANES VII) data. A total of 12,689 participants aged over 19 received a periodontal examination among the 24,269 participants of KNHANES VII. Diagnosed depression and self-reported depression symptom were the two terms used for depression. Periodontitis was defined as the presence of teeth with periodontal pockets of 4 mm or deeper. The age, sex, marital status, education, region, basic livelihood protection, private health insurance, type of housing, health insurance coverage, household income, sleeping hours, subjective health condition, stress perception, drinking status, obesity, and current smoking status of the participants were examined. Chi-square tests and two-tailed analyses were used. The association of depression and periodontitis was tested by using logistic regression models adjusted for socio-demographic and behavioral variables. Diagnosed depression was associated with periodontitis, as the odds ratio of diagnosed depression for periodontitis was 1.772 (95% confidence interval = 1.328-2.364). However, the association between self-reported depression symptom and periodontitis was not statistically significant. This study revealed that diagnosed depression, not self-reported depression symptom, could be a risk factor for periodontitis. Therefore, it is necessary to take a closer look into diagnosed depression in order to manage and prevent periodontitis.
抑郁会损害免疫防御机制,并且由于牙周病病原体的积累,可能会使牙周炎恶化。本研究旨在利用韩国国民健康营养调查 7 号(KNHANES VII)的数据,探讨经诊断的抑郁症和自我报告的抑郁症状与牙周炎之间的关联。在 KNHANES VII 的 24269 名参与者中,共有 12689 名年龄在 19 岁以上的参与者接受了牙周检查。诊断性抑郁症和自我报告的抑郁症状是抑郁症的两个术语。牙周炎的定义是存在牙周袋深度为 4 毫米或更深的牙齿。检查了参与者的年龄、性别、婚姻状况、教育程度、地区、基本生活保障、私人健康保险、住房类型、医疗保险覆盖范围、家庭收入、睡眠时间、主观健康状况、压力感知、饮酒状况、肥胖和当前吸烟状况。使用卡方检验和双尾分析。使用调整了社会人口统计学和行为变量的逻辑回归模型测试了抑郁与牙周炎之间的关联。诊断性抑郁症与牙周炎有关,因为诊断性抑郁症患牙周炎的比值比为 1.772(95%置信区间= 1.328-2.364)。然而,自我报告的抑郁症状与牙周炎之间的关联没有统计学意义。本研究表明,诊断性抑郁症而不是自我报告的抑郁症状可能是牙周炎的一个危险因素。因此,有必要更深入地了解诊断性抑郁症,以管理和预防牙周炎。