韩国成年人中吸烟与饮酒水平和牙周炎存在情况的交互关联。
The interactive association of smoking and drinking levels with presence of periodontitis in South Korean adults.
作者信息
Lee Mira, Choi Yoon-Hyeong, Sagong Jun, Yu Sol, Kim Yongbae, Lee Dongjae, Kim Sungroul
机构信息
Department of Environmental Health Sciences, Soonchunhyang University, Soonchunhyang-Ro 22, Asan, Chungnam, 336-745, South Korea.
Graduate School of Medicine, Gachon University, Incheon, South Korea.
出版信息
BMC Oral Health. 2016 Aug 25;16(1):80. doi: 10.1186/s12903-016-0268-y.
BACKGROUND
Periodontitis is a chronic and long-lasting low-grade inflammatory disease. Numerous studies have shown that the severity of periodontitis rose when there was an increase in the amount of smoking or alcohol consumption. However, as periodontitis known as a chronic disease, it is important to consider not only the amount but "duration" with frequency i.e., rates, of smoking or drinking. This study assessed impacts of the amount and duration of smoking and drinking on periodontal health in Korean adults. We also investigated whether or not there is an interactive effect of smoking and drinking on periodontal health.
METHODS
Under a cross-sectional study design, we used data from the fourth and fifth the Korean National Health and Nutrition Examination Survey (KNHANES) sessions (2008-2010). A total of 18,488 subjects (over 19 years) answered both smoking and drinking status and were given the periodontal examination. Periodontal health status was determined by the community periodontal index (CPI) developed by the World Health Organization (WHO). According to the WHO guidelines, if a participant's CPI was 3 or larger, we classified the person as a case of periodontitis. Participants with a CPI < 3 were assigned to the control group.
RESULTS
Prevalence of periodontitis for self-reported smokers or drinkers in South Korea was 35.0 or 28.0 %, respectively. We observed 1.20 (0.931.56) of odds ratio (95 % CI) for prevalence (POR) of periodontitis for those smoked <13 pack-year (PY) and drank ≥6.8 glass-year (GY). And we had POR of 1.91 (1.342.73) for those smoked ≥13 PY and drank <6.8 GY, compared to those nonsmoking nondrinkers. The observed POR of 2.41 (95 % CI: 1.94-3.00), for those smoked ≥13 PY and drank ≥6.8 GY, was higher than a multiplicative effect estimated, i.e., 1.20 (0.931.56) [those smoked <13 PY and drank ≥6.8 GY] × 1.91 (1.342.73) [those smoked ≥13 PY and drank <6.8 GY], or 2.29.
CONCLUSIONS
We observed a multiplicative interactive effect of smoking and drinking on periodontal status among Korean adults.
背景
牙周炎是一种慢性、持久的低度炎症性疾病。大量研究表明，吸烟量或饮酒量增加时，牙周炎的严重程度会上升。然而，由于牙周炎是一种慢性病，不仅要考虑吸烟或饮酒的量，还要考虑其“持续时间”以及频率，即吸烟或饮酒的速率。本研究评估了韩国成年人吸烟和饮酒的量与持续时间对牙周健康的影响。我们还调查了吸烟和饮酒对牙周健康是否存在交互作用。
方法
在横断面研究设计下，我们使用了韩国国家健康与营养检查调查（KNHANES）第四轮和第五轮（2008 - 2010年）的数据。共有18488名受试者（19岁以上）回答了吸烟和饮酒状况，并接受了牙周检查。牙周健康状况由世界卫生组织（WHO）制定的社区牙周指数（CPI）确定。根据WHO指南，如果参与者的CPI为3或更高，我们将其归类为牙周炎病例。CPI < 3的参与者被分配到对照组。
结果
韩国自我报告的吸烟者或饮酒者中，牙周炎的患病率分别为35.0%或28.0%。我们观察到，对于吸烟量<13包年（PY）且饮酒量≥6.8杯年（GY）的人，牙周炎患病率的优势比（OR）为1.20（0.931.56）（95%置信区间）。与不吸烟不饮酒者相比，吸烟量≥13 PY且饮酒量<6.8 GY的人，牙周炎患病率的优势比为1.91（1.342.73）。对于吸烟量≥13 PY且饮酒量≥6.8 GY的人，观察到的优势比为2.41（95%置信区间：1.94 - 3.00），高于估计的相乘效应，即1.20（0.931.56）[吸烟量<13 PY且饮酒量≥6.8 GY的人]×1.91（1.342.73）[吸烟量≥13 PY且饮酒量<6.8 GY的人]，即2.29。
结论
我们观察到吸烟和饮酒对韩国成年人的牙周状况存在相乘交互作用。
Zotero 插件