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维生素 D 缺乏与韩国≥60 岁成年人牙周炎的关系:来自韩国国家健康和营养检查调查(2013-2014 年)的数据分析。

Relationship between Vitamin D Deficiency and Periodontitis in Korean Adults Aged ≥60 Years: Analysis of Data from the Korea National Health and Nutrition Examination Survey (2013-2014).

机构信息

Department of Dental Hygiene, Hanseo University, Seosan 31962, Korea.

Department of Dental Hygiene, College of Health Science, Gachon University, Incheon 21936, Korea.

出版信息

Int J Environ Res Public Health. 2021 Apr 15;18(8):4181. doi: 10.3390/ijerph18084181.

DOI:10.3390/ijerph18084181
PMID:33920903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8071325/
Abstract

There have been contradictory reports on the effects of vitamin D in the prevention of periodontitis. We analyzed the association between vitamin D status (levels of plasma 25(OH)D) and periodontitis using the Korea National Health and Nutrition Examination Survey (KNHANES) 2013-2014 database. Among the participants in the KNHANES (2013-2014), only those aged ≥60 years who completed a health interview survey, periodontal examination, and blood test were included in the study. Thus, data from 701 participants were used in the final analysis. Periodontal status was evaluated using the Community Periodontal Index (CPI), and periodontitis was defined as having a CPI score of 3 or 4. Plasma 25(OH)D levels were classified according to two criteria: 20 ng/mL and quartile value. The chi-square test and multivariate logistic regression analyses were performed to analyze the prevalence of periodontitis according to plasma 25(OH)D levels. Univariate analyses showed that periodontitis was not significantly associated with plasma 25(OH)D levels. In the multivariate logistic regression model adjusted for sociodemographic characteristics, the difference in the prevalence of periodontitis between those with a normal range of 25(OH)D and those with low plasma of 25(OH)D levels was not statistically significant. Vitamin D intake has been reported to have benefits in maintaining periodontal health; however, total plasma 25(OH)D levels showed no significant association with periodontitis based on CPI scores in this study. Additionally, these findings reaffirmed the importance of toothbrushing and smoking cessation to prevent periodontitis in people aged ≥60 years.

摘要

关于维生素 D 在预防牙周炎方面的作用,已有相互矛盾的报告。我们使用 2013-2014 年韩国国家健康和营养调查(KNHANES)数据库分析了维生素 D 状态(血浆 25(OH)D 水平)与牙周炎之间的关联。在 KNHANES(2013-2014 年)的参与者中,仅纳入完成健康访谈调查、牙周检查和血液检查且年龄≥60 岁的人群进行研究。因此,最终分析中使用了 701 名参与者的数据。牙周状况使用社区牙周指数(CPI)进行评估,将 CPI 评分为 3 或 4 的情况定义为牙周炎。根据两个标准将血浆 25(OH)D 水平分类:20ng/ml 和四分位值。采用卡方检验和多变量逻辑回归分析,根据血浆 25(OH)D 水平分析牙周炎的患病率。单变量分析显示,牙周炎与血浆 25(OH)D 水平无显著相关性。在调整了社会人口学特征的多变量逻辑回归模型中,25(OH)D 正常范围和低血浆 25(OH)D 水平者之间牙周炎患病率的差异无统计学意义。有报道称,维生素 D 摄入有益于维持牙周健康;然而,根据本研究中 CPI 评分,总血浆 25(OH)D 水平与牙周炎之间无显著关联。此外,这些发现再次证实了对于≥60 岁的人群,刷牙和戒烟对于预防牙周炎非常重要。

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本文引用的文献

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Could Vitamin D influence risk for Periodontal Disease - to "D" or not to "D"?维生素D会影响患牙周病的风险吗——是“维D”还是“无维D”?
Curr Oral Health Rep. 2020 Mar;7(1):98-111. doi: 10.1007/s40496-020-00253-7. Epub 2020 Jan 20.
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Environmental and Occupation Factors Associated with Vitamin D Deficiency in Korean Adults: The Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2014.环境和职业因素与韩国成年人维生素 D 缺乏相关:韩国国家健康和营养检查调查(KNHANES)2010-2014 年。
Int J Environ Res Public Health. 2020 Dec 8;17(24):9166. doi: 10.3390/ijerph17249166.
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Hand motor functions on the presence of red fluorescent dental biofilm in older community-dwelling Koreans.手部运动功能与老年社区居住韩国人口腔内红色荧光牙菌斑的存在有关。
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Periodontal Disease, Systemic Inflammation and the Risk of Cardiovascular Disease.牙周病、全身炎症与心血管疾病风险
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