Ashiru-Oredope Diane, Kerr Frances, Hughes Stephen, Urch Jonathan, Lanzman Marisa, Yau Ting, Cockburn Alison, Patel Rakhee, Sheikh Adel, Gormley Cairine, Chavda Aneeka, Vaghela Tejal, Phillips Ceri, Reid Nicholas, Brady Aaron
The Pharmacy Infection Network (PIN), United Kingdom Clinical Pharmacy Association (UKCPA), Leicester LE2 5BB, UK.
Association of Scottish Antimicrobial Pharmacists, Scotland ML6 8ES, UK.
Antibiotics (Basel). 2021 Jan 23;10(2):110. doi: 10.3390/antibiotics10020110.
Since first identified in late 2019, the acute respiratory syndrome coronavirus (SARS-CoV2) and the resulting coronavirus disease (COVID-19) pandemic has overwhelmed healthcare systems worldwide, often diverting key resources in a bid to meet unprecedented challenges. To measure its impact on national antimicrobial stewardship (AMS) activities, a questionnaire was designed and disseminated to antimicrobialstewardship leads in the United Kingdom (UK). Most respondents reported a reduction in AMS activity with 64% (61/95) reporting that COVID-19 had a negative impact on routine AMS activities. Activities reported to have been negatively affected by the pandemic include audit, quality improvement initiatives, education, AMS meetings, and multidisciplinary working including ward rounds. However, positive outcomes were also identified, with technology being increasingly used as a tool to facilitate stewardship e.g., virtual meetings and ward rounds and increased the acceptance of using procalcitonin tests to distinguish between viral and bacterial infections. The COVID-19 pandemic has had a significant impact on the AMS activities undertaken across the UK. The long-term impact of the reduced AMS activities on incidence of AMR are not yet known. The legacy of innovation, use of technology, and increased collaboration from the pandemic could strengthen AMS in the post-pandemic era and presents opportunities for further development of AMS.
自2019年末首次被发现以来，急性呼吸综合征冠状病毒（SARS-CoV2）以及由此引发的冠状病毒病（COVID-19）大流行已使全球医疗系统不堪重负，为应对前所未有的挑战，关键资源常常被挪用。为衡量其对国家抗菌药物管理（AMS）活动的影响，设计了一份调查问卷并分发给英国的抗菌药物管理负责人。大多数受访者报告称AMS活动有所减少，64%（61/95）的受访者表示COVID-19对常规AMS活动产生了负面影响。据报告，受疫情负面影响的活动包括审计、质量改进举措、教育、AMS会议以及包括查房在内的多学科协作。然而，也发现了积极成果，技术越来越多地被用作促进管理的工具，例如虚拟会议和查房，并提高了使用降钙素原检测来区分病毒感染和细菌感染的接受度。COVID-19大流行对英国开展的AMS活动产生了重大影响。AMS活动减少对耐药性发生率的长期影响尚不清楚。疫情带来的创新、技术应用以及加强合作的成果，可能会在后疫情时代加强AMS，并为AMS的进一步发展带来机遇。
