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长期循环使用基于马桶的尿液分析样本收集器。

Long-term cyclic use of a sample collector for toilet-based urine analysis.

机构信息

Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269, USA.

Department of Mechanical Engineering, University of Connecticut, Storrs, CT, 06269, USA.

出版信息

Sci Rep. 2021 Jan 26;11(1):2170. doi: 10.1038/s41598-021-81842-z.

Abstract

Urine analysis via a toilet-based device can enable continuous health monitoring, a transformation away from hospital-based care towards more proactive medicine. To enable reliable sample collection for a toilet-attached analyzer, here a novel sample collector is proposed. The applicability of the proposed sample collector is validated for long-term use. Geometric parameters of the 3D-printed sample collector are optimized. The collected and leftover volumes are quantified for a range of urination speeds and design parameters. For long-term cyclic use, the protein concentrations of samples are quantified and the effectiveness of washing the sample collector is assessed.

摘要

基于马桶的尿液分析设备可以实现连续的健康监测,使医疗从以医院为基础的护理模式转变为更具主动性的医疗模式。为了实现与马桶相连的分析器可靠的样本采集,这里提出了一种新型的样本采集器。验证了所提出的样本采集器的长期使用适用性。对 3D 打印样本采集器的几何参数进行了优化。针对不同的排尿速度和设计参数,对采集的样本量和剩余样本量进行了定量分析。为了进行长期循环使用,对样本中的蛋白质浓度进行了定量,并评估了清洗样本采集器的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86d1/7838403/6fa1ed8aa0d9/41598_2021_81842_Fig1_HTML.jpg

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