Kosaka T, Sawada T, Ichikawa S
Department of Animal Reproduction, College of Agriculture, University of Osaka Prefecture, Japan.
Experientia. 1988 Jan 15;44(1):43-5. doi: 10.1007/BF01960239.
Differences in the secretion of pregnane compounds from rats with follicular polycystic ovaries under constant light and with normal preovulatory ovaries under light-dark conditions were compared. The injection of LH greatly increased the secretion of progesterone. 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one, in both types of ovaries, but the response of the two progesterone metabolites in the polycystic ovaries was low, suggesting low 5 alpha-reductase activity.
