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Endogenous inhibitor of ecdysone synthesis in crabs.

作者信息

Naya Y, Kishida K, Sugiyama M, Murata M, Miki W, Ohnishi M, Nakanishi K

机构信息

Suntory Institute for Bioorganic Research, Osaka, Japan.

出版信息

Experientia. 1988 Jan 15;44(1):50-2. doi: 10.1007/BF01960242.

DOI:10.1007/BF01960242
PMID:3350119
Abstract

Attempts to isolate the molt-inhibiting hormone (MIH) of crustaceans from crab eyestalks (ES) resulted in the characterization of xanthurenic acid as an inhibitor of ecdysone biosynthesis in the cultured Y-organ-complex (YOC) homogenate. It was also found that 3-hydroxy-L-kynurenine present in the ES is transformed into xanthurenic acid in the YOC and body fluid. Its mode of inhibitory action in ecdysone biosynthesis is probably inactivation of cytochrome P-450.

摘要

相似文献

1
Endogenous inhibitor of ecdysone synthesis in crabs.
Experientia. 1988 Jan 15;44(1):50-2. doi: 10.1007/BF01960242.
2
Physiological role of 3-hydroxykynurenine and xanthurenic acid upon crustacean molting.3-羟基犬尿氨酸和黄尿酸对甲壳类动物蜕皮的生理作用。
Adv Exp Med Biol. 1991;294:309-18. doi: 10.1007/978-1-4684-5952-4_28.
3
Involvement of cAMP and cGMP in the mode of action of molt-inhibiting hormone (MIH) a neuropeptide which inhibits steroidogenesis in a crab.环磷酸腺苷（cAMP）和环磷酸鸟苷（cGMP）参与蜕皮抑制激素（MIH，一种抑制蟹类类固醇生成的神经肽）的作用模式。
Mol Cell Endocrinol. 1994 Jun;102(1-2):53-61. doi: 10.1016/0303-7207(94)90097-3.
4
Regulation of Y-organ ecdysteroidogenesis by molt-inhibiting hormone in crabs: involvement of cyclic AMP-mediated protein synthesis.蜕皮抑制激素对蟹类Y器官蜕皮类固醇生成的调节：环磷酸腺苷介导的蛋白质合成的参与
Gen Comp Endocrinol. 1986 Sep;63(3):414-23. doi: 10.1016/0016-6480(86)90141-3.
5
What is molt-inhibiting hormone? The role of an ecdysteroidogenesis inhibitor in the crustacean molting cycle.什么是蜕皮抑制激素？蜕皮甾类激素抑制剂在甲壳动物蜕皮周期中的作用。
Proc Natl Acad Sci U S A. 1989 Sep;86(17):6826-9. doi: 10.1073/pnas.86.17.6826.
6
Ecdysone and retinoid-X receptors of the blue crab, Callinectes sapidus: cloning and their expression patterns in eyestalks and Y-organs during the molt cycle.蓝蟹（Callinectes sapidus）蜕皮激素和视黄酸 X 受体：克隆及其在蜕皮周期中眼柄和 Y 器官中的表达模式。
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Stress reduces hemolymph ecdysteroid levels in the crab: mediation by the eyestalks.应激会降低螃蟹血淋巴中的蜕皮类固醇水平：通过眼柄介导。
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Secretion of alpha-ecdysone by crab Y-organs in vitro.蟹Y器官在体外分泌α-蜕皮激素。
Proc Natl Acad Sci U S A. 1977 Feb;74(2):615-8. doi: 10.1073/pnas.74.2.615.

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What is molt-inhibiting hormone? The role of an ecdysteroidogenesis inhibitor in the crustacean molting cycle.什么是蜕皮抑制激素？蜕皮甾类激素抑制剂在甲壳动物蜕皮周期中的作用。
Proc Natl Acad Sci U S A. 1989 Sep;86(17):6826-9. doi: 10.1073/pnas.86.17.6826.

本文引用的文献

1
[On the chemistry of ecdysone. VI. Reactions of ecdysone molecules].[关于蜕皮激素的化学。VI. 蜕皮激素分子的反应]
Chem Ber. 1965 Jul;98(7):2394-402. doi: 10.1002/cber.19650980743.
2
Endocrine control of reproduction in decapod Crustacea.
Biol Rev Camb Philos Soc. 1970 May;45(2):121-65. doi: 10.1111/j.1469-185x.1970.tb01627.x.
3
Neurohormonal control of ecdysteroid biosynthesis by Carcinus maenas Y-organs in vitro, and preliminary characterization of the putative molt-inhibiting hormone (MIH).体外研究食蟹猴Y器官对蜕皮甾体生物合成的神经激素控制以及假定的蜕皮抑制激素（MIH）的初步特性分析
Gen Comp Endocrinol. 1986 Feb;61(2):237-47. doi: 10.1016/0016-6480(86)90201-7.
4
Functional relations of crab molt-inhibiting hormone and neurohypophysial peptides.
Peptides. 1985 Jul-Aug;6(4):635-40. doi: 10.1016/0196-9781(85)90166-4.
5
The qualitative and quantitative determinations of ecdysones in tissues of the crab, Pachygrapsus crassipes, following molt induction.
Gen Comp Endocrinol. 1976 Sep;30(1):21-33. doi: 10.1016/0016-6480(76)90062-9.
6
Molt-inhibiting factor from the crustacean eyestalk.来自甲壳类动物眼柄的蜕皮抑制因子。
Gen Comp Endocrinol. 1977 Feb;31(2):233-42. doi: 10.1016/0016-6480(77)90022-3.
7
[Metabolism of ecdysone in several organs of Carcinus maenas L. incubated in vitro].
C R Acad Hebd Seances Acad Sci D. 1976 Nov 15;283(12):1445-8.
8
In vitro secretion and hydroxylation of alpha-ecdysone as a function of the crustacean molt cycle.α-蜕皮激素的体外分泌和羟基化与甲壳动物蜕皮周期的关系。
Gen Comp Endocrinol. 1978 Sep;36(1):151-10. doi: 10.1016/0016-6480(78)90060-6.
9
Secretion of alpha-ecdysone by crab Y-organs in vitro.蟹Y器官在体外分泌α-蜕皮激素。
Proc Natl Acad Sci U S A. 1977 Feb;74(2):615-8. doi: 10.1073/pnas.74.2.615.