Couto Maria Eduarda, Oliveira Isabel, Mariz Mário, Ferraz Gonçalves José
Onco-Hematology Service.
Palliative Care Service, Instituto Português de Oncologia do Porto FG, EPE, Porto, Portugal.
Porto Biomed J. 2019 Oct 28;4(6):e39. doi: 10.1097/j.pbj.0000000000000039. eCollection 2019 Nov-Dec.
Most of the palliative care (PC) patients have oncologic diseases, being hematologic tumors a small part of them. According to the literature, onco-hematologic (OH) patients should be individualized from those with solid tumors for the specialized care required along their disease course. This study aims to review the casuistry of OH patients referred to PC in a specialized oncologic hospital and help to understand better how hematologists can improve the care of these patients.
We analyzed all OH patients referred to the PC service in 1 oncologic hospital along 42 months, through consultation of their clinical files.
A total of 179 patients were reviewed (52.% males, median age of 71 years): 48.6% had non-Hodgkin lymphoma, 26.3% had multiple myeloma, 10.6% had acute leukemia, 14.5% had other OH diseases; 88.2% were treated for their OH disease (96.2% with chemotherapy, 28.5% radiotherapy, and 21.5% hematopoietic stem cell transplant). The referral was heterogeneous among physicians (27.4% by 1 physician). Most patients were firstly observed as inpatients (55.3%) and 17.9% in the outpatient consult. At the end of the study, 98.9% of the patients died (88.7% in the hospital, 10.2% at home). The median time between the end of treatment and referral do PC was 46 days and between referral and death was 16 days. We also reviewed medical prescription in the last month of life and we noticed that most invasive orders were requested by hematologists (as antibiotic prescription, imaging, and biopsy studies).
This study demonstrated that OH patients should be referred earlier to PC and that a more intensive team work needs to be practiced between PC and hematologists. More educational programs for healthcare workers on this issue are needed in order to guarantee a more effective assistance in the appropriate time.
大多数姑息治疗(PC)患者患有肿瘤疾病,血液系统肿瘤仅占其中一小部分。根据文献,血液肿瘤(OH)患者因其疾病过程中所需的专科护理,应与实体瘤患者区分开来。本研究旨在回顾一家专科肿瘤医院中被转诊至PC的OH患者的情况,并有助于更好地理解血液科医生如何改善对这些患者的护理。
我们通过查阅42个月内一家肿瘤医院中所有被转诊至PC服务的OH患者的临床档案进行分析。
共审查了179例患者(52%为男性,中位年龄71岁):48.6%患有非霍奇金淋巴瘤,26.3%患有多发性骨髓瘤,10.6%患有急性白血病,14.5%患有其他OH疾病;88.2%的患者接受了OH疾病治疗(96.2%接受化疗,28.5%接受放疗,21.5%接受造血干细胞移植)。医生之间的转诊情况各异(27.4%由1位医生转诊)。大多数患者首先以住院患者身份接受观察(55.3%),17.9%在门诊咨询时接受观察。研究结束时,98.9%的患者死亡(88.7%在医院死亡,10.2%在家中死亡)。治疗结束至转诊至PC的中位时间为46天,转诊至死亡的中位时间为16天。我们还回顾了患者生命最后一个月的医疗处方,发现大多数侵入性医嘱是由血液科医生开出的(如抗生素处方、影像学检查和活检研究)。
本研究表明,OH患者应更早转诊至PC,并且PC团队与血液科医生之间需要开展更密切的协作。需要针对医护人员开展更多关于此问题的教育项目,以确保在适当时间提供更有效的援助。