Yang Li, Tan Liping, Liu Tongjun
Department of Bioengineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, Shandong, China.
State Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, Shandong, China.
Sheng Wu Gong Cheng Xue Bao. 2021 Jan 25;37(1):15-29. doi: 10.13345/j.cjb.200221.
Lignocellulose can be hydrolyzed by cellulase into fermentable sugars to produce hydrogen, ethanol, butanol and other biofuels with added value. Pretreatment is a critical step in biomass conversion, but also generates inhibitors with negative impacts on subsequent enzymatic hydrolysis and fermentation. Hence, pretreatment and detoxification methods are the basis of efficient biomass conversion. Commonly used pretreatment methods of lignocellulose are chemical and physic-chemical processes. Here, we introduce different inhibitors and their inhibitory mechanisms, and summarize various detoxification methods. Moreover, we propose research directions for detoxification of inhibitors generated during lignocellulose pretreatment.
木质纤维素可被纤维素酶水解为可发酵糖,以生产氢气、乙醇、丁醇和其他具有附加值的生物燃料。预处理是生物质转化中的关键步骤,但也会产生对后续酶水解和发酵有负面影响的抑制剂。因此,预处理和解毒方法是高效生物质转化的基础。常用的木质纤维素预处理方法是化学和物理化学过程。在此,我们介绍不同的抑制剂及其抑制机制,并总结各种解毒方法。此外,我们还提出了木质纤维素预处理过程中产生的抑制剂解毒的研究方向。