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最初阴性患者中随后出现的严重急性呼吸综合征冠状病毒 2 逆转录聚合酶链反应阳性的发生和时间。

Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients.

机构信息

Division of Critical Care Medicine, Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.

Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

出版信息

Clin Infect Dis. 2021 Jan 27;72(2):323-326. doi: 10.1093/cid/ciaa722.

Abstract

Using data for 20 912 patients from 2 large academic health systems, we analyzed the frequency of severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and was similar across institutions.

摘要

使用来自 2 个大型学术医疗系统的 20912 名患者的数据,我们分析了在最初通过鼻咽拭子检测为阴性的个体中,基于临床原因在 7 天内再次检测时出现严重急性呼吸综合征冠状病毒 2 逆转录聚合酶链反应检测不一致的频率。在此窗口期内后续检测呈阳性的频率为 3.5%,并且在各个机构之间相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544b/7840103/1e5ea86c47fd/ciaa722_fig1.jpg

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