手术部位感染与手术抗生素预防的新进展？
WHAT'S NEW IN INFECTION ON SURGICAL SITE AND ANTIBIOTICOPROPHYLAXIS IN SURGERY?
机构信息
Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil.
出版信息
Arq Bras Cir Dig. 2021 Jan 25;33(4):e1558. doi: 10.1590/0102-672020200004e1558. eCollection 2021.
INTRODUCTION
Infection of the surgical site is the common complication, with significant rates of morbidity and mortality, representing a considerable economic problem for the health system.
OBJECTIVE
To carry out a narrative review of the literature on surgical site infection and the principles of antibiotic prophylaxis to update the knowledge of its use in surgery.
METHOD
Medline, Ovid, Google Scholar, National Library of Medicine (PubMed), Cochrane and SciELO were used for the research. The keywords used were "anti-bacterial agents"; "antibioticoprophylaxis" AND "surgical wound infection". The inclusion criteria were articles of recent publication, with full texts available and performed in humans.
RESULT
A total of 29 articles were evaluated and selected according to the eligibility criteria.
CONCLUSION
Infection of the surgical site is the most common postoperative complication. The key point of its prevention is the combination of several interventions that aim to reduce risk factors, such as: compliance with the new guidelines of the Center for Disease Control and Prevention; the principles of the use of prophylactic antibiotics; factors and risk index of the surgical site; administration time; duration and dosage of antibiotics. These data are available in this article.
引言
手术部位感染是一种常见的并发症，具有较高的发病率和死亡率，给医疗系统带来了巨大的经济负担。
目的
对手术部位感染和抗生素预防原则的文献进行叙述性综述，以更新其在外科手术中应用的相关知识。
方法
使用 Medline、Ovid、Google Scholar、美国国家医学图书馆（PubMed）、Cochrane 和 SciELO 数据库进行检索。使用的关键词为“抗菌剂”；“抗生素预防”和“手术部位感染”。纳入标准为近期发表的全文可用的人类研究文章。
结果
根据纳入标准，共评估和选择了 29 篇文章。
结论
手术部位感染是最常见的术后并发症。预防感染的关键在于结合多种干预措施，旨在降低风险因素，例如：遵循疾病控制与预防中心的新指南；预防性使用抗生素的原则；手术部位的危险因素和风险指数；给药时间；抗生素的持续时间和剂量。本文提供了这些数据。
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