Thorn C, Faber A, Schultz J D, Hörmann K, Stuck B A
Universitäts-HNO-Klinik Mannheim der Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68157, Mannheim, Deutschland,
HNO. 2015 Feb;63(2):118-24. doi: 10.1007/s00106-014-2946-x.
Surgical antibiotic prophylaxis (SAP) is defined as the administration of an antimicrobial agent prior to contamination in previously sterile spaces and fluid. SAP should not be confused with the therapeutic use of antibiotics. There are a growing number of studies with the goal of answering the question which patients benefit most from SAP during which specific surgical procedure. However, in the specific surgical field of head and neck surgery and otolaryngological surgery, there are only a few guidelines answering that question for specific procedures. The aim of this study was to analyze the evidence found in the literature and to develop a standard operating procedure, which specifically addresses head and neck and otolaryngeal surgical procedures.
外科手术预防性抗生素应用（SAP）的定义是在先前无菌的空间和液体受到污染之前给予抗菌药物。不应将SAP与抗生素的治疗用途相混淆。为回答哪些患者在特定外科手术过程中从SAP中获益最大这一问题而开展的研究越来越多。然而，在头颈外科和耳鼻喉科这一特定外科领域，针对特定手术回答该问题的指南却很少。本研究的目的是分析文献中发现的证据，并制定一份标准操作规程，专门针对头颈和耳鼻喉外科手术。
