Laboratorio de Adaptacoes Cardiovasculares ao Exercicio (LACORE), Universidade Federal do Maranhao, Sao Luis, MA, BR.
Programa de Pos-Graduacao em Educacao Fisica, Universidade Federal do Maranhao, Sao Luis, MA, BR.
Clinics (Sao Paulo). 2021 Jan 20;76:e1826. doi: 10.6061/clinics/2021/e1826. eCollection 2021.
We compared the autonomic modulation and sleep behavior of eutrophic and overweight patients with chronic obstructive pulmonary disease (COPD).
COPD participants were divided into the overweight and eutrophic groups. Pulmonary function, blood pressure, body composition, autonomic modulation, and the Pittsburgh Sleep Quality Index score were assessed. Participants performed the six-minute walk test for functional assessment.
Spirometric variables obtained in eutrophic and overweight individuals with COPD showed no statistically different results. We observed that the SDNN index indicated lower overall variability (p=0.003), and root mean square of successive differences between normal heart beats (RMSSD) (p=0.04) indicated lower parasympathetic modulation in the overweight group than observed in the eutrophic group. The indexes of the frequency domain presented lower values of total variability (p<0.01), low frequency bands (p<0.01), and high frequency (p=0.02), suggesting a higher sympathetic modulation and reduced parasympathetic modulation of the overweight group compared to eutrophic group. The overweight group also showed reduced sleep quality than the eutrophic group.
Overweight COPD patients showed lower autonomic modulation and impaired sleep quality, latency, and efficiency as compared eutrophic subjects. These results reinforce the importance of weight control and the acquisition of healthy habits in this population.
比较肥胖和超重的慢性阻塞性肺疾病（COPD）患者的自主神经调节和睡眠行为。
将 COPD 患者分为超重组和非超重组。评估肺功能、血压、身体成分、自主神经调节和匹兹堡睡眠质量指数评分。参与者进行六分钟步行测试以进行功能评估。
非超重和超重 COPD 患者的肺功能变量结果无统计学差异。我们观察到，SDNN 指数表示整体变异性降低（p=0.003），正常心跳之间的均方根差（RMSSD）（p=0.04）表示超重组的副交感神经调节低于非超重组。频域指数显示总变异性（p<0.01）、低频带（p<0.01）和高频带（p=0.02）的较低值，表明与非超重组相比，超重组的交感神经调节增加，副交感神经调节减少。超重组的睡眠质量也低于非超重组。
与非超重患者相比，超重的 COPD 患者的自主神经调节降低，睡眠质量、潜伏期和效率受损。这些结果强调了控制体重和养成健康习惯对这一人群的重要性。
