单细胞测序技术揭示了胰腺胰岛细胞的异质性。
Patch-seq shows the heterogeneity of pancreatic islet cells.
机构信息
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
出版信息
J Diabetes Investig. 2021 May;12(5):691-693. doi: 10.1111/jdi.13514. Epub 2021 Feb 25.
Abstract
In 2016, Patch-seq was established to analyze electrophysiology, gene expression and morphology in neuronal cells. Recently, Camunas-Soler et al. used Patch-seq to analyze the functions and gene expression profiles of individual cells in pancreatic islets. I believe this analysis is expected to contribute to the complete characterization of pancreatic islets in diabetes patients.
摘要
2016 年，Patch-seq 技术被建立用于分析神经元细胞的电生理、基因表达和形态。最近，Camunas-Soler 等人使用 Patch-seq 技术分析了胰岛中单个细胞的功能和基因表达谱。我相信这种分析有望促进对糖尿病患者胰岛的全面特征描述。
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