Antigen Presentation by B Cells in Multiple Sclerosis.
作者信息
Zamvil Scott S, Hauser Stephen L
机构信息
From the UCSF Weill Institute for Neurosciences, Department of Neurology (S.S.Z., S.L.H.), and the Program in Immunology, University of California, San Francisco (S.S.Z) - both in San Francisco.
出版信息
N Engl J Med. 2021 Jan 28;384(4):378-381. doi: 10.1056/NEJMcibr2032177.
Abstract
摘要
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本文引用的文献
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2
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3
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Science. 2019 Sep 27;365(6460). doi: 10.1126/science.aav7188.
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