Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States.
Department of Biostatistics, University of Michigan, Ann Arbor, MI, United States.
J Affect Disord. 2021 Mar 15;283:1-10. doi: 10.1016/j.jad.2021.01.030. Epub 2021 Jan 13.
Individuals with bipolar disorder (BD) show different personality profiles compared to non-psychiatric populations, but little is known about the temporal stability of personality traits over time, and if changes in mood state drive changes in personality.
Participants were 533 BD and 185 healthy controls (HC) who completed the NEO-Personality Inventory-Revised (NEO-PI-R) and clinician-administered measures of mood at baseline. One-hundred-eighty BD and 79 HC completed the measures at 5-year follow-up and 60 BD and 16 HC completed the measures at 10-year follow-up. The above measures and demographic information, but not other clinical status indicators the BD illness, were used in analyses.
The BD group has higher Neuroticism (N)/N facets and lower Extraversion (E)/E facets and Consciousness (C)/C facets compared to HC. Significant mean-level changes existed within groups but were small in magnitude, and groups showed similar moderate-to-high rank-order stability. Change in (N)/N facets shows an association with change in depression, but changes in all other NEO-PI-R scores are not associated with changes in mood. Personality traits are clinically stable in part of our bipolar sample using clinically relevant interpretation of changes in T scores; however, some BD subjects did show more reliable changes in personality traits than the healthy controls.
Reliance on self-report measurement and not all our participants completed the 5- and 10-year follow-up personality assessment who were eligible to do so.
Mean-level and rank-order personality scores show only modest changes, so most personality changes over time are not systematic. Observed changes in personality traits are not explained by changes in mood with the exception of Neuroticism, suggesting other factors influence changes in personality.
与非精神病患者群体相比，双相情感障碍（BD）患者表现出不同的人格特征，但人们对人格特质随时间的稳定性知之甚少，也不知道情绪状态的变化是否会导致人格的变化。
共有 533 名 BD 和 185 名健康对照（HC）参与者完成了 NEO 人格量表修订版（NEO-PI-R）和临床医生评估的情绪量表。180 名 BD 和 79 名 HC 在 5 年随访时完成了这些测量，60 名 BD 和 16 名 HC 在 10 年随访时完成了这些测量。上述测量和人口统计学信息，但不包括 BD 疾病的其他临床状态指标，都用于分析。
BD 组的神经质（N）/N 因子和外向性（E）/E 因子以及意识（C）/C 因子得分均高于 HC。组内存在显著的平均水平变化，但幅度较小，组间表现出相似的中高度等级稳定性。（N）/N 因子的变化与抑郁的变化有关，但其他所有 NEO-PI-R 得分的变化与情绪的变化无关。使用 T 分数变化的临床相关解释，我们部分双相样本中的人格特质具有临床稳定性；然而，一些 BD 患者的人格特质变化比健康对照组更可靠。
依赖于自我报告的测量，并非所有符合条件的参与者都完成了 5 年和 10 年的随访人格评估。
平均水平和等级顺序人格得分仅略有变化，因此大多数随时间的人格变化不是系统性的。除了神经质外，人格特质的观察到的变化不能用情绪的变化来解释，这表明其他因素影响人格的变化。
