[海南百岁老人血脂谱分布特征]

[Distribution characteristics of blood lipid profile in Hainan centenarians].

作者信息

Wang S S, Yang S S, Jia W P, Cao W Z, Han K, Li J, Tai P G, Kou F Y, Zhao Y L, Zhu Q, Ning C X, Liu M, He Y

机构信息

Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital,Beijing 100853, China；Health Service Department, the Fifth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100853, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Jan 10;42(1):80-87. doi: 10.3760/cma.j.cn112338-20200424-00636.

DOI:10.3760/cma.j.cn112338-20200424-00636

PMID:33503701

Abstract

To explore the prevalence of lipid profile and the influencing factors of dyslipidemia in centenarians in Hainan province, and provide basic data for the study of the lipid profile in centenarians. The data of this study were from the baseline data of China Hainan Centenarian Cohort Study from June 2014 to December 2016. A total of 1 002 centenarians were recruited. According to the guidelines for the prevention and treatment of dyslipidemia in Chinese adults in 2016, the prevalence of lipid profile were described and the prevalence of dyslipidemia with different clinical classifications were compared, and the main influencing factors were analyzed. The median levels of TC, TG, LDL-C and HDL-C were 4.60 mmol/L, 1.05 mmol/L, 2.77 mmol/L and 1.41 mmol/L, respectively, in centenarians in Hainan. Blood lipid profile level was higher in females than in males. With the increase of BMI, TC, TG and LDL-C increased significantly, while HDL-C decreased significantly. The total prevalence of dyslipidemia was 19.1%. Smoking, BMI and area distribution were the main influencing factors of dyslipidemia. The prevalence of dyslipidemia in centenarians in Hainan was at a low level compared with other countries, and the blood lipid profile level was higher in females than in males.

摘要

为探讨海南省百岁老人血脂谱的流行情况及血脂异常的影响因素，为百岁老人血脂谱研究提供基础数据。本研究数据来源于2014年6月至2016年12月中国海南百岁老人队列研究的基线数据。共招募了1002名百岁老人。根据2016年中国成人血脂异常防治指南，描述血脂谱的流行情况，比较不同临床分类的血脂异常患病率，并分析主要影响因素。海南百岁老人的总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）和高密度脂蛋白胆固醇（HDL-C）的中位数水平分别为4.60 mmol/L、1.05 mmol/L、2.77 mmol/L和1.41 mmol/L。女性血脂谱水平高于男性。随着体重指数（BMI）的增加，TC、TG和LDL-C显著升高，而HDL-C显著降低。血脂异常的总患病率为19.1%。吸烟、BMI和地区分布是血脂异常的主要影响因素。与其他国家相比，海南百岁老人血脂异常患病率处于较低水平，且女性血脂谱水平高于男性。