Distribution of blood glucose and prevalence of diabetes among centenarians and oldest-old in China: based on the China Hainan Centenarian Cohort Study and China Hainan Oldest-old Cohort Study.

OBJECTIVE

There was little data on the distribution of blood glucose levels and diabetes prevalence for centenarians and the oldest-old. The aim of this study is to analyzed the distribution of blood glucose and diabetes prevalence for centenarians and oldest-old in China: Based on the China Hainan Centenarian Cohort Study (CHCCS) and China Hainan Oldest-old Cohort Study (CHOCS).

DESIGN

A cross-sectional study.

SETTING AND PARTICIPANTS

A total of 1002 centenarians and 798 oldest-old were enrolled from 18 cities and counties in Hainan Province (one of the longevity provinces) from 2016-2018.

MEASURES

The fasting blood glucose was tested and prevalence of diabetes was calculated.

RESULTS

The average age of centenarians was 102.77 ± 2.55 years old, 82.0% were women. The average age of the oldest-old was 84.99 ± 4.01 years old, 59.9% were women. The average blood glucose of centenarians was 5.12 ± 1.44 and 4.80 ± 1.27 mmol/L, and more than 70% were between 3.00 mmol/L and 5.99 mmol/L. There was no statistical difference between different genders and age groups. A total of 9.5% of centenarians had diabetes and 8.1% had IFG. A total of 11.4% of the oldest-old had diabetes and 4.4% had IFG. Abdominal obesity and TG levels may be associated with diabetes prevalence. The corresponding ORs were 1.517(1.083-2.125) and 1.473(1.089-1.943) respectively of abdominal obesity among centenarians and the oldest-old respectively, and corresponding ORs 1.182(1.081-1.316) and 1.162(1.009-1.699) respectively of abdominal obesity among centenarians and the oldest-old respectively CONCLUSIONS AND IMPLICATIONS: In summary, the results based on CHCCS with the largest sample among centenarians and CHOCS showed that the blood glucose level and the prevalence of diabetes were at a lower level than those of adults or younger elderly. The results provide new evidence for target level of blood glucose control in those older elderly.