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牛至提取物增强斑马鱼生长性能、血清和黏液先天免疫反应及对[病原体名称未给出]攻击的抵抗力。

Oregano () Extract Enhances Zebrafish () Growth Performance, Serum and Mucus Innate Immune Responses and Resistance against Challenge.

作者信息

Rashidian Ghasem, Boldaji Javad Tahmasebi, Rainis Simona, Prokić Marko D, Faggio Caterina

机构信息

Department of Aquaculture, Faculty of Marine Sciences, Tarbiat Modares University, Noor 4641776489, Iran.

Dipartimento di Scienze Biomolecolare (DISB), Facoltà di Farmacia, Università degli Studi di Urbino "Carlo Bo", Via Aurelio Saffi 2, 61029 Urbino, PU, Italy.

出版信息

Animals (Basel). 2021 Jan 25;11(2):299. doi: 10.3390/ani11020299.

DOI:10.3390/ani11020299
PMID:33503883
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7912135/
Abstract

This study evaluated the dietary effects of an ultrasound-assisted extract of on the growth, antioxidant and immune responses (serum and mucosal) and resistance of zebrafish () against . Four hundred and forty adult zebrafish were distributed into 12 tanks and fed 4 experimental diets including 0% (control), 0.5% (M1), 1% (M2) and 2% (M3) of the extract per kg diet for eight weeks. Fish were then challenged with and mortality was recorded for 10 days. Results revealed that the extract exerted potent effects on growth parameters of weight gain and specific growth rate. The feed conversion ratio was significantly lower in fish fed extract-incorporated diets. extract improved antioxidant and immune responses, resulting in less sensitivity to oxidative stress and a higher survival rate when challenged with . Overall, the greatest effects were observed in individuals with 1% dietary inclusion of the extract. These results suggest that the extract from the plant possesses a great potential to be used in the aquaculture industry and that zebrafish is an appropriate model for nutrition studies.

摘要

本研究评估了[植物名称]超声辅助提取物的日粮对斑马鱼([斑马鱼学名])生长、抗氧化和免疫反应(血清和黏膜)以及抵抗[病原体名称]能力的影响。440条成年斑马鱼被分配到12个水箱中,投喂4种实验日粮,分别为每千克日粮含0%(对照)、0.5%(M1)、1%(M2)和2%(M3)的提取物,持续8周。然后用[病原体名称]对鱼进行攻毒,并记录10天的死亡率。结果显示,该提取物对增重和特定生长率等生长参数有显著影响。在投喂含提取物日粮的鱼中,饲料转化率显著更低。[植物名称]提取物改善了抗氧化和免疫反应,使其在受到[病原体名称]攻毒时对氧化应激的敏感性降低,存活率更高。总体而言,日粮中提取物添加量为1%时效果最佳。这些结果表明,[植物名称]提取物在水产养殖业中具有很大的应用潜力,并且斑马鱼是营养研究的合适模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f3/7912135/06109faa39d3/animals-11-00299-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f3/7912135/b5f6b4ff7ac6/animals-11-00299-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f3/7912135/06109faa39d3/animals-11-00299-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f3/7912135/b5f6b4ff7ac6/animals-11-00299-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f3/7912135/06109faa39d3/animals-11-00299-g002.jpg

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