Kim Myung Soo, Jung Seung Il
Department of Urology, Chonnam National University Medical School, Gwangju, Korea.
Int Neurourol J. 2021 Mar;25(1):3-11. doi: 10.5213/inj.2040174.087. Epub 2021 Jan 19.
The human body is sterile during gestation; however, but during and after birth, the entire body surface becomes host to an enormous variety of microorganisms. Urine in the urinary tract was once considered sterile based on the lack of cultured microorganisms. Many recent studies have revealed evidence of microorganisms in human urine in the absence of clinical infection. Sequencing methods and analytical techniques are rapidly evolving to improve the ability to detect bacterial DNA and living bacteria and to understand the microbiota of the urinary tract. In women, fascinating evidence associates urinary tract microbiota with lower urinary tract symptoms. However, in men, the relevance of urinary tract microbiota in low urinary tract symptoms and prostate disease has not been established. In this review, we highlight a recent study that increases our ability to understand the urinary tract microbiota in men with lower urinary tract symptoms.
在妊娠期，人体是无菌的；然而，在出生期间及之后，整个体表会成为大量微生物的宿主。基于培养不出微生物，泌尿道中的尿液曾被认为是无菌的。最近许多研究揭示了在无临床感染情况下人体尿液中存在微生物的证据。测序方法和分析技术正在迅速发展，以提高检测细菌DNA和活细菌的能力，并了解泌尿道的微生物群。在女性中，有引人关注的证据表明泌尿道微生物群与下尿路症状有关。然而，在男性中，泌尿道微生物群在低尿路症状和前列腺疾病中的相关性尚未确立。在本综述中，我们重点介绍了一项最近的研究，该研究增强了我们对患有下尿路症状男性的泌尿道微生物群的理解能力。
