Department of Computer Engineering & Applications GLA University, 17km Stone, NH-2, Mathura-Delhi Road Mathura, Chaumuhan, Uttar Pradesh-281406, India.
Institute of Pharmaceutical Research GLA University, 17km Stone, NH-2, Mathura-Delhi Road Mathura, Chaumuhan, Uttar Pradesh-281406, India.
Curr Pharm Biotechnol. 2021;22(12):1591-1601. doi: 10.2174/1389201022666210127113441.
Coronavirus-19 is a severe acute respiratory disorder in humans which has become a major health problem. It spreads out very rapidly throughout the world since it has been first identified in Wuhan, China (December 2019). The causative virus is known as severe acute respiratory syndrome coronavirus 2. And the World Health Organization has named this respiratory syndrome as a new epidemic disease called COVID-19. The incidence of COVID-19 continued to increase with three million confirmed infected cases and with 244,000 death cases worldwide. Until now there is no specific treatment or vaccine available against COVID- 19. The collective information about the different aspects of COVID-19 viral infection has been gathered from renowned journals, and electronic databases including Science Direct, Web of Science, Scopus and PubMed from 1990 to 2020. This manuscript has highlighted the transmission and symptoms of Covid-19. Therefore, these studies show how the SARS-CoV 2 can facilitate the debut of the virus into targeted host cells.
新型冠状病毒肺炎（Coronavirus-19）是一种严重的急性呼吸道疾病，已成为一个主要的健康问题。自 2019 年 12 月在中国武汉首次发现以来，该病毒迅速在全球范围内传播。引起该疾病的病毒被称为严重急性呼吸系统综合征冠状病毒 2 型。世界卫生组织（World Health Organization）将这种呼吸系统综合征命名为一种新的传染病，称为 COVID-19。全球确诊感染人数持续增加，达 300 万例，死亡人数达 24.4 万例。到目前为止，还没有针对 COVID-19 的特定治疗方法或疫苗。从 1990 年到 2020 年，从著名期刊和电子数据库（包括 Science Direct、Web of Science、Scopus 和 PubMed）中收集了关于 COVID-19 病毒感染的不同方面的综合信息。本文强调了 COVID-19 的传播和症状。因此，这些研究表明了 SARS-CoV-2 如何促进病毒进入目标宿主细胞。
