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超氧化物歧化酶的等电聚焦:美国白人群体中独特的SOD A*2等位基因报告。

Isoelectric focusing of superoxide dismutase: report of the unique SOD A*2 allele in a US white population.

作者信息

DeCroo S, Kamboh M I, Leppert M, Ferrell R E

机构信息

Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pa.

出版信息

Hum Hered. 1988;38(1):1-7. doi: 10.1159/000153745.

Abstract

An isoelectric focusing procedure in an ultranarrow pH range (5.0-5.5) polyacrylamide gel is described for the determination of superoxide dismutase (SOD) phenotypes. The occurrence of the rare SOD A*2 allele in the Caucasian population of Utah is also reported at a polymorphic frequency (0.011). The presence of the SOD A 2 unique allele in the Mormons of Utah is compatible with their historical affinity with Scandinavians.

摘要

描述了一种在超窄pH范围(5.0 - 5.5)聚丙烯酰胺凝胶中进行等电聚焦的方法,用于测定超氧化物歧化酶(SOD)表型。还报道了在犹他州的白种人群体中罕见的SOD A*2等位基因以多态频率(0.011)出现。犹他州摩门教徒中存在SOD A 2独特等位基因,这与他们与斯堪的纳维亚人在历史上的亲缘关系相符。

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