Saeed Ghufran Aref, Gaba Waqar, Shah Asad, Al Helali Abeer Ahmed, Raidullah Emadullah, Al Ali Ameirah Bader, Elghazali Mohammed, Ahmed Deena Yousef, Al Kaabi Shaikha Ghanam, Almazrouei Safaa
Department of Radiology, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Department of Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Radiol Res Pract. 2021 Jan 6;2021:6697677. doi: 10.1155/2021/6697677. eCollection 2021.
Our aim is to correlate the clinical condition of patients with COVID-19 infection with the 25-point CT severity score by Chang et al. (devised for assessment of ARDS in patients with SARS in 2005).
Data of consecutive symptomatic patients who were suspected to have COVID-19 infection and presented to our hospital were collected from March to April 2020. All patients underwent two consecutive RT-PCR tests and had a noncontrast HRCT scan done at presentation. From the original cohort of 1062 patients, 160 patients were excluded leaving a total number of 902 patients.
The mean age was 44.2 ± 11.9 years (85.3% males, 14.7% females). CT severity score was found to be positively correlated with lymphopenia, increased serum CRP, d-dimer, and ferritin levels ( < 0.0001). The oxygen requirements and length of hospital stay were increasing with the increase in scan severity.
The 25-point CT severity score correlates well with the COVID-19 clinical severity. Our data suggest that chest CT scoring system can aid in predicting COVID-19 disease outcome and significantly correlates with lab tests and oxygen requirements.
我们的目的是将新型冠状病毒肺炎（COVID-19）感染患者的临床状况与Chang等人制定的25分CT严重程度评分（该评分于2005年用于评估严重急性呼吸综合征（SARS）患者的急性呼吸窘迫综合征（ARDS））相关联。
收集2020年3月至4月期间我院疑似感染COVID-19的连续有症状患者的数据。所有患者均接受了两次连续的逆转录聚合酶链反应（RT-PCR）检测，并在就诊时进行了非增强高分辨率计算机断层扫描（HRCT）。在最初的1062例患者队列中，排除了160例患者，最终共有902例患者。
平均年龄为44.2±11.9岁（男性占85.3%，女性占14.7%）。发现CT严重程度评分与淋巴细胞减少、血清C反应蛋白（CRP）、D-二聚体和铁蛋白水平升高呈正相关（<0.0001）。随着扫描严重程度的增加，氧气需求量和住院时间也在增加。
25分CT严重程度评分与COVID-19的临床严重程度密切相关。我们的数据表明，胸部CT评分系统有助于预测COVID-19疾病的预后，并且与实验室检查和氧气需求量显著相关。
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