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木村病:单侧扁桃体肿大的罕见病因。

Kimura's Disease: A Rare Cause of Unilateral Tonsillar Enlargement.

作者信息

Khanal Prakash, Shrestha Agya

机构信息

Nepal Police Hospital, Maharajgunj, Kathmandu, Nepal.

出版信息

Case Rep Otolaryngol. 2021 Jan 7;2021:8815317. doi: 10.1155/2021/8815317. eCollection 2021.

Abstract

INTRODUCTION

Kimura's disease is a rare inflammatory disorder of unknown cause, commonly seen in young Asian males. . A 61-year-old male patient presented with a history of right tonsillar mass and cervical lymphadenopathy. The patient underwent hematological investigation and imaging followed by resection of tonsillar mass. Based on histopathological and subsequent immunohistochemistry reports, the case was diagnosed as Kimura's disease of the tonsil. . Kimura's disease commonly presents as painless subcutaneous masses in the head and neck region or cervical lymphadenopathy. Kimura's disease presenting as a tonsillar mass is a very rare condition. Patients usually have peripheral eosinophilia and elevated levels of serum IgE. The diagnosis is based on the clinical and histopathologic findings in a biopsy of the mass and/or lymph node along with elevated peripheral eosinophil and serum IgE level.

CONCLUSION

The clinical presentation of Kimura's disease is highly variable. Kimura's disease should be considered as a differential diagnosis in patients presenting with a tonsillar mass. A high index of suspicion along with histopathological examination helps in the early diagnosis and management. Surgical excision is the treatment of choice.

摘要

引言

木村病是一种病因不明的罕见炎症性疾病,常见于年轻亚洲男性。一名61岁男性患者有右侧扁桃体肿物及颈部淋巴结病病史。患者接受了血液学检查和影像学检查,随后切除了扁桃体肿物。根据组织病理学及后续免疫组化报告,该病例被诊断为扁桃体木村病。木村病通常表现为头颈部无痛性皮下肿物或颈部淋巴结病。以扁桃体肿物形式出现的木村病是一种非常罕见的情况。患者通常有外周血嗜酸性粒细胞增多及血清IgE水平升高。诊断基于肿物和/或淋巴结活检的临床及组织病理学表现,以及外周血嗜酸性粒细胞增多和血清IgE水平升高。

结论

木村病的临床表现高度多变。对于出现扁桃体肿物的患者,应将木村病作为鉴别诊断考虑。高度怀疑并结合组织病理学检查有助于早期诊断和治疗。手术切除是首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c8d/7808821/d645e4c3d641/CRIOT2021-8815317.001.jpg

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